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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Ullah, Riaz
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (7/7 displayed)
- 2024Nanozyme-based sensing of dopamine using cobalt-doped hydroxyapatite nanocomposite from waste bonescitations
- 2024Chitosan, chitosan derivatives, and chitosan-based nanocomposites: eco-friendly materials for advanced applications (a review)citations
- 2024From Waste to Sensor: Facile Synthesis of a Copper‐Doped Hydroxyapatite Nanocomposite as a Colorimetric Sensing Platform for Uric Acidcitations
- 2023Optimization and antifungal efficacy against brown rot fungi of combined Salvia rosmarinus and Cedrus atlantica essential oils encapsulated in Gum Arabiccitations
- 2022Removal of Doxycycline from Water using Dalbergia sissoo Waste Biomass Based Activated Carbon and Magnetic Oxide/Activated Bioinorganic Nanocomposite in Batch Adsorption and Adsorption/Membrane Hybrid Processescitations
- 2020Isolation of Quercetin from Rubus fruticosus, Their Concentration through NF/RO Membranes, and Recovery through Carbon Nanocomposite. A Pilot Plant Studycitations
- 2019Separation of Levofloxacin from Industry Effluents Using Novel Magnetic Nanocomposite and Membranes Hybrid Processescitations
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article
From Waste to Sensor: Facile Synthesis of a Copper‐Doped Hydroxyapatite Nanocomposite as a Colorimetric Sensing Platform for Uric Acid
Abstract
<jats:title>Abstract</jats:title><jats:p>Uric acid serves as a vital diagnostic marker for diseases like arthritis, gout, etc. Accurate quantification of UA is crucial for diagnosis. The hydroxyapatite (HAp), being catalytic in nature, was used as a template for copper nanoparticles (CuNPs) synthesis and for providing surface area for chemical reactions needed for sensing uric acid. HAp was synthesized from waste chicken bones, followed by doping with copper metal salt through calcination. The synthesis of copper hydroxyapatite (Cu‐HAp) nanocomposite was confirmed using different techniques. SEM displayed the nanoporous morphology of the material. The hexagonal crystal structure of HAp was revealed by X‐ray diffraction analysis, and energy dispersive X‐ray analysis showed the successful doping of Cu on HAp. The Cu‐HAp nanocomposite and 3,3′,5,5′‐tetramethylbenzidine (TMB) dye were employed as a new colorimetric sensing platform for uric acid sensing. The fabricated sensing platform detected uric acid with excellent sensitivity (LOD, 0.24 μM) and a wide linear range (1–270 μM). Optimization experiments demonstrated that the proposed sensor performs best at 4 mg of Cu‐HAp nanocomposite, pH 6, with a response time of 100 s. Furthermore, TMB and H<jats:sub>2</jats:sub>O<jats:sub>2</jats:sub> concentrations of 12 and 8 mM were used, respectively. The proposed sensor successfully detected uric acid in physiological samples.</jats:p>