| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Knowles, Jonathan C.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (33/33 displayed)
- 2024Titanium-doped phosphate glasses containing zinc and strontium applied in bone regeneration
- 2024A sol-gel templating route for the synthesis of hierarchical porous calcium phosphate glasses containing zinccitations
- 20243D Melt-Extrusion Printing of Medium Chain Length Polyhydroxyalkanoates and Their Application as Antibiotic-Free Antibacterial Scaffolds for Bone Regenerationcitations
- 2023Biodegradable and Sustainable Synthetic Antibodies—A Perspective
- 2021Antibacterial Composite Materials Based on the Combination of Polyhydroxyalkanoates With Selenium and Strontium Co-substituted Hydroxyapatite for Bone Regenerationcitations
- 2020Modulation of neuronal cell affinity of composite scaffolds based on polyhydroxyalkanoates and bioactive glassescitations
- 2018Binary polyhydroxyalkanoate systems for soft tissue engineeringcitations
- 2016Composite scaffolds for cartilage tissue engineering based on natural polymers of bacterial origin, thermoplastic poly(3‐hydroxybutyrate) and micro‐fibrillated bacterial cellulosecitations
- 2016P(3HB) Based Magnetic Nanocomposites: Smart Materials for Bone Tissue Engineeringcitations
- 2015Novel sol–gel preparation of (P2O5)0.4–(CaO)0.25–(Na2O)X–(TiO2)(0.35−X) bioresorbable glasses (X = 0.05, 0.1, and 0.15)citations
- 2015Titanium phosphate glass microcarriers induce enhanced osteogenic cell proliferation and human mesenchymal stem cell protein expressioncitations
- 2013Aspirin-loaded P(3HO)/P(3HB) blend films: potential materials for biodegradable drug-eluting stentscitations
- 2012Novel Biodegradable and Biocompatible Poly(3‐hydroxyoctanoate)/Bacterial Cellulose Compositescitations
- 2012Structural characterization of titanium-doped Bioglass using isotopic substitution neutron diffractioncitations
- 2012Structural characterization and physical properties of P2O5-CaO-Na2O-TiO2 glasses by Fourier transform infrared, Raman and solid-state magic angle spinning nuclear magnetic resonance spectroscopies.citations
- 2012Titanium phosphate glass microspheres for bone tissue engineering.citations
- 2010Tailoring Cell Behavior on Polymers by the Incorporation of Titanium Doped Phosphate Glass Fillercitations
- 2010Poly(3-hydroxybutyrate) multifunctional composite scaffolds for tissue engineering applications.citations
- 2010<i>In vitro</i> studies on the influence of surface modification of Ni–Ti alloy on human bone cellscitations
- 2010Reactive calcium-phosphate-containing poly(ester-co-ether) methacrylate bone adhesives: chemical, mechanical and biological considerations.citations
- 2009A study of the formation of amorphous calcium phosphate and hydroxyapatite on melt quenched Bioglass(A (R)) using surface sensitive shallow angle X-ray diffractioncitations
- 2009Structure and properties of strontium-doped phosphate-based glassescitations
- 2009Incorporation of vitamin E in poly(3hydroxybutyrate)/Bioglass composite films: effect on surface properties and cell attachment.citations
- 2009Doping of a high calcium oxide metaphosphate glass with titanium dioxidecitations
- 2008Structural characteristics of antibacterial bioresorbable phosphate glasscitations
- 2008A high-energy X-ray diffraction, P-31 and B-11 solid-state NMR study of the structure of aged sodium borophosphate glassescitations
- 2008An X-ray absorption spectroscopy study of the local environment of iron in degradable iron-phosphate glassescitations
- 2008Comparison of nanoscale and microscale bioactive glass on the properties of P(3HB)/Bioglass composites.citations
- 2007The structure and properties of silver-doped phosphate-based glassescitations
- 2007The structure of phosphate glass biomaterials from neutron diffraction and 31P nuclear magnetic resonance datacitations
- 2006Initial responses of human osteoblasts to sol-gel modified titanium with hydroxyapatite and titania composition.citations
- 2006X-ray absorption spectroscopy and high-energy XRD study of the local environment of copper in antibacterial copper-releasing degradable phosphate glassescitations
- 2006Initial responses of human osteoblasts to sol–gel modified titanium with hydroxyapatite and titania composition
Places of action
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article
Composite scaffolds for cartilage tissue engineering based on natural polymers of bacterial origin, thermoplastic poly(3‐hydroxybutyrate) and micro‐fibrillated bacterial cellulose
Abstract
Cartilage tissue engineering is an emerging therapeutic strategy that aims to regenerate damaged cartilage caused by disease, trauma, ageing or developmental disorder. Since cartilage lacks regenerative capabilities, it is essential to develop approaches that deliver the appropriate cells, biomaterials and signalling factors to the defect site. Materials and fabrication technologies are therefore critically important for cartilage tissue engineering in designing temporary, artificial extracellular matrices (scaffolds), which support 3D cartilage formation. Hence, this work aimed to investigate the use of poly(3-hydroxybutyrate)/microfibrillated bacterial cellulose (P(3HB)/MFC) composites as 3D-scaffolds for potential application in cartilage tissue engineering. The compression moulding/particulate leaching technique employed in the study resulted in good dispersion and a strong adhesion between the MFC and the P(3HB) matrix. Furthermore, the composite scaffold produced displayed better mechanical properties than the neat P(3HB) scaffold. On addition of 10, 20, 30 and 40 wt% MFC to the P(3HB) matrix, the compressive modulus was found to have increased by 35%, 37%, 64% and 124%, while the compression yield strength increased by 95%, 97%, 98% and 102% respectively with respect to neat P(3HB). Both cell attachment and proliferation were found to be optimal on the polymer-based 3D composite scaffolds produced, indicating a non-toxic and highly compatible surface for the adhesion and proliferation of mouse chondrogenic ATDC5 cells. The large pores sizes (60-83 mu m) in the 3D scaffold allowed infiltration and migration of ATDC5 cells deep into the porous network of the scaffold material. Overall this work confirmed the potential of P(3HB)/MFC composites as novel materials in cartilage tissue engineering.