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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Sack, I.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (23/23 displayed)
- 2024On the relationship between viscoelasticity and water diffusion in soft biological tissues.citations
- 2022Mechanical behavior of the hippocampus and corpus callosum: An attempt to reconcile ex vivo with in vivo and micro with macro properties.citations
- 2021Real-Time Multifrequency MR Elastography of the Human Brain Reveals Rapid Changes in Viscoelasticity in Response to the Valsalva Maneuver.citations
- 2020Cardiac-gated steady-state multifrequency magnetic resonance elastography of the brain: Effect of cerebral arterial pulsation on brain viscoelasticity.citations
- 2019Sensitivity of multifrequency magnetic resonance elastography and diffusion-weighted imaging to cellular and stromal integrity of liver tissue.citations
- 2018Combining viscoelasticity, diffusivity and volume of the hippocampus for the diagnosis of Alzheimer's disease based on magnetic resonance imaging.citations
- 2015Tabletop magnetic resonance elastography for the measurement of viscoelastic parameters of small tissue samples.citations
- 2014High-resolution mechanical imaging of the kidney.citations
- 2014Wideband MRE and static mechanical indentation of human liver specimen: sensitivity of viscoelastic constants to the alteration of tissue structure in hepatic fibrosis.citations
- 2014In vivo time-harmonic multifrequency elastography of the human liver.citations
- 2013Compression-sensitive magnetic resonance elastography.citations
- 2013Isovolumetric elasticity alteration in the human heart detected by in vivo time-harmonic elastography.citations
- 2012Fractal network dimension and viscoelastic powerlaw behavior: I. A modeling approach based on a coarse-graining procedure combined with shear oscillatory rheometry.citations
- 2010Viscoelasticity-based MR elastography of skeletal muscle.citations
- 2010Viscoelasticity-based staging of hepatic fibrosis with multifrequency MR elastography.citations
- 2010Viscoelastic properties of liver measured by oscillatory rheometry and multifrequency magnetic resonance elastography.citations
- 2008Non-invasive measurement of brain viscoelasticity using magnetic resonance elastography.citations
- 2008Assessment of liver viscoelasticity using multifrequency MR elastography.citations
- 2007Three-dimensional analysis of shear wave propagation observed by in vivo magnetic resonance elastography of the brain.citations
- 2007Noninvasive assessment of the rheological behavior of human organs using multifrequency MR elastography: a study of brain and liver viscoelasticity.citations
- 2006Shear wave group velocity inversion in MR elastography of human skeletal muscle.citations
- 2003Electromagnetic actuator for generating variably oriented shear waves in MR elastography.citations
- 2002Analysis of wave patterns in MR elastography of skeletal muscle using coupled harmonic oscillator simulations.
Places of action
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article
Non-invasive measurement of brain viscoelasticity using magnetic resonance elastography.
Abstract
The purpose of this work was to develop magnetic resonance elastography (MRE) for the fast and reproducible measurement of spatially averaged viscoelastic constants of living human brain. The technique was based on a phase-sensitive echo planar imaging acquisition. Motion encoding was orthogonal to the image plane and synchronized to intracranial shear vibrations at driving frequencies of 25 and 50 Hz induced by a head-rocker actuator. Ten time-resolved phase-difference wave images were recorded within 60 s and analyzed for shear stiffness and shear viscosity. Six healthy volunteers (six men; mean age 34.5 years; age range 25-44 years) underwent 23-39 follow-up MRE studies over a period of 6 months. Interindividual mean +/- SD shear moduli and shear viscosities were found to be 1.17 +/- 0.03 kPa and 3.1 +/- 0.4 Pas for 25 Hz and 1.56 +/- 0.07 kPa and 3.4 +/- 0.2 Pas for 50 Hz, respectively (P < or = 0.01). The intraindividual range of shear modulus data was 1.01-1.31 kPa (25 Hz) and 1.33-1.77 kPa (50 Hz). The observed modulus dispersion indicates a limited applicability of Voigt's model to explain viscoelastic behavior of brain parenchyma within the applied frequency range. The narrow distribution of data within small confidence intervals demonstrates excellent reproducibility of the experimental protocol. The results are necessary as reference data for future comparisons between healthy and pathological human brain viscoelastic data.