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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Braun, Jürgen
Charité - Universitätsmedizin Berlin
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (26/26 displayed)
- 2022Mechanical behavior of the hippocampus and corpus callosum: An attempt to reconcile ex vivo with in vivo and micro with macro properties.citations
- 2020Diagnostic performance of tomoelastography of the liver and spleen for staging hepatic fibrosiscitations
- 2019Sensitivity of multifrequency magnetic resonance elastography and diffusion-weighted imaging to cellular and stromal integrity of liver tissue.citations
- 2019Surface resonance of thin films of the Heusler half-metal Co2MnSi probed by soft x-ray angular resolved photoemission spectroscopy
- 2018Signature of a highly spin polarized resonance state at $mathrm{Co_{2}MnSi(0 0 1)/Ag(0 0 1)}$ interfacescitations
- 2018Combining viscoelasticity, diffusivity and volume of the hippocampus for the diagnosis of Alzheimer's disease based on magnetic resonance imaging.citations
- 2018Signature of a highly spin polarized resonance state at Co2MnSi(001)/Ag(001) interfaces
- 2017Vectorial spin polarization detection in multichannel spin-resolved photoemission spectroscopy using an Ir(001) imaging spin filtercitations
- 2015Cerebral multifrequency MR elastography by remote excitation of intracranial shear wavescitations
- 2015Tabletop magnetic resonance elastography for the measurement of viscoelastic parameters of small tissue samples.citations
- 2014High-resolution mechanical imaging of the kidney.citations
- 2014In vivo multifrequency magnetic resonance elastography of the human intervertebral diskcitations
- 2014In vivo time-harmonic multifrequency elastography of the human liver.citations
- 2013Compression-sensitive magnetic resonance elastography.citations
- 2013Isovolumetric elasticity alteration in the human heart detected by in vivo time-harmonic elastography.citations
- 2012Fractal network dimension and viscoelastic powerlaw behavior: I. A modeling approach based on a coarse-graining procedure combined with shear oscillatory rheometry.citations
- 2012Monitoring the formation of interface-confined mixture by photoelectron spectroscopycitations
- 2010Viscoelasticity-based MR elastography of skeletal muscle.citations
- 2010Viscoelastic properties of liver measured by oscillatory rheometry and multifrequency magnetic resonance elastography.citations
- 2008Non-invasive measurement of brain viscoelasticity using magnetic resonance elastography.citations
- 2008Diffusive diffraction observed with volume-selective STEAM MRS in 100microm water-filled capillaries.
- 2007Three-dimensional analysis of shear wave propagation observed by in vivo magnetic resonance elastography of the brain.citations
- 2007Noninvasive assessment of the rheological behavior of human organs using multifrequency MR elastography: a study of brain and liver viscoelasticity.citations
- 2006Shear wave group velocity inversion in MR elastography of human skeletal muscle.citations
- 2003Electromagnetic actuator for generating variably oriented shear waves in MR elastography.citations
- 2002Analysis of wave patterns in MR elastography of skeletal muscle using coupled harmonic oscillator simulations.
Places of action
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article
Non-invasive measurement of brain viscoelasticity using magnetic resonance elastography.
Abstract
The purpose of this work was to develop magnetic resonance elastography (MRE) for the fast and reproducible measurement of spatially averaged viscoelastic constants of living human brain. The technique was based on a phase-sensitive echo planar imaging acquisition. Motion encoding was orthogonal to the image plane and synchronized to intracranial shear vibrations at driving frequencies of 25 and 50 Hz induced by a head-rocker actuator. Ten time-resolved phase-difference wave images were recorded within 60 s and analyzed for shear stiffness and shear viscosity. Six healthy volunteers (six men; mean age 34.5 years; age range 25-44 years) underwent 23-39 follow-up MRE studies over a period of 6 months. Interindividual mean +/- SD shear moduli and shear viscosities were found to be 1.17 +/- 0.03 kPa and 3.1 +/- 0.4 Pas for 25 Hz and 1.56 +/- 0.07 kPa and 3.4 +/- 0.2 Pas for 50 Hz, respectively (P < or = 0.01). The intraindividual range of shear modulus data was 1.01-1.31 kPa (25 Hz) and 1.33-1.77 kPa (50 Hz). The observed modulus dispersion indicates a limited applicability of Voigt's model to explain viscoelastic behavior of brain parenchyma within the applied frequency range. The narrow distribution of data within small confidence intervals demonstrates excellent reproducibility of the experimental protocol. The results are necessary as reference data for future comparisons between healthy and pathological human brain viscoelastic data.