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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Xu, Chunlin
Åbo Akademi University
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (23/23 displayed)
- 2024Employing photocurable biopolymers to engineer photosynthetic 3D-printed living materials for production of chemicalscitations
- 2023Semi-solid 3D printing of mesoporous silica nanoparticle-incorporated xeno-free nanomaterial hydrogels for protein deliverycitations
- 2022Injectable thiol-ene hydrogel of galactoglucomannan and cellulose nanocrystals in delivery of therapeutic inorganic ions with embedded bioactive glass nanoparticlescitations
- 2022Injectable thiol-ene hydrogel of galactoglucomannan and cellulose nanocrystals in delivery of therapeutic inorganic ions with embedded bioactive glass nanoparticlescitations
- 2022Digital light processing (DLP) 3D-fabricated antimicrobial hydrogel with a sustainable resin of methacrylated woody polysaccharides and hybrid silver-lignin nanospherescitations
- 2021On Laccase-Catalyzed Polymerization of Biorefinery Lignin Fractions and Alignment of Lignin Nanoparticles on the Nanocellulose SurfaceviaOne-Pot Water-Phase Synthesiscitations
- 2021Bio-Based Hydrogels With Ion Exchange Properties Applied to Remove Cu(II), Cr(VI), and As(V) Ions From Watercitations
- 2021Removal of nafcillin sodium monohydrate from aqueous solution by hydrogels containing nanocellulosecitations
- 2021On Laccase-Catalyzed Polymerization of Biorefinery Lignin Fractions and Alignment of Lignin Nanoparticles on the Nanocellulose Surface via One-Pot Water-Phase Synthesiscitations
- 2021Removal of nafcillin sodium monohydrate from aqueous solution by hydrogels containing nanocellulose:An experimental and theoretical studycitations
- 2020Tailored thermosetting wood adhesive based on well-defined hardwood lignin fractionscitations
- 2020Electrospinning of Electroconductive Water-Resistant Nanofibers of PEDOTPSS, Cellulose Nanofibrils and PEO: Fabrication Characterization, and Cytocompatibilitycitations
- 2020Electrospinning of Electroconductive Water-Resistant Nanofibers of PEDOTPSS, Cellulose Nanofibrils and PEO: Fabrication Characterization, and Cytocompatibilitycitations
- 2018Novel biorenewable composite of wood polysaccharide and polylactic acid for three dimensional printingcitations
- 2017Conducting ink based on cellulose nanocrystals and polyaniline for flexographical printingcitations
- 2017Mild oxalic-acid-catalyzed hydrolysis as a novel approach to prepare cellulose nanocrystalscitations
- 2016Development of nanocellulose scaffolds with tunable structures to support 3D cell culturecitations
- 2015Tailor-made hemicellulose-based hydrogels reinforced with nanofibrillated cellulosecitations
- 2015Strong reinforcing effects from galactoglucomannan hemicellulose on mechanical behavior of wet cellulose nanofiber gelscitations
- 2015Composite films of nanofibrillated cellulose and O-acetyl galactoglucomannan (GGM) coated with succinic esters of GGM showing potential as barrier material in food packagingcitations
- 2015Conductivity of PEDOT:PSS on spin-coated and drop cast nanofibrillar cellulose thin filmscitations
- 2014Biocomposites of Nanofibrillated Cellulose, Polypyrrole, and Silver Nanoparticles with Electroconductive and Antimicrobial Propertiescitations
- 2008Kinetics of acid hydrolysis of water-soluble spruce O-acetyl galactoglucomannanscitations
Places of action
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article
Semi-solid 3D printing of mesoporous silica nanoparticle-incorporated xeno-free nanomaterial hydrogels for protein delivery
Abstract
ultifunctional biomaterial inks are in high demand for adapting hydrogels in biomedical applications through three-dimensional (3D) printing. Our previously developed xeno-free system consisting of anionic cellulose nanofibers (T-CNF) and methacrylated galactoglucomannan (GGMMA) as a photo(bio)polymer provides high-performance ink fidelity in extrusion-based 3D printing. The fusion between nanoparticles and this biomaterial-ink system is a promising yet challenging avenue worth exploring, due to the colloidal stability of T-CNF being sensitive to electrostatic interactions. Mesoporous silica nanoparticles (MSNs), with their robust ceramic matrix and fine-tunable surface chemistries, are well-established nanocarriers for different biologicals. Here, we fabricated MSNs with different surface modifications resulting in a net surface charge ranging from highly negative to highly positive to develop printable MSNs-laden nanocomposite biomaterial inks. We utilized rheology as a comprehensive tool to address the matrix interactions with differently surface-charged MSNs. Fluorescently labeled bovine serum albumin (FITC-BSA) was used as a model protein for MSN loading, whereby negatively or neutral-charged MSNs were found suitable to formulate FITC-BSA-loaded biomaterial inks of T-CNF/GGMMA. Depending on the particles’ surface charge, FITC-BSA showed different release profiles and preserved its stability after release. Lastly, the proof-of-concept to deliver large-sized biological cargo with MSN-laden nanocomposite biomaterial inks was established via the 3D printing technique.