| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Rosenholm, Jessica M.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2023Advancement in Solubilization Approaches: A Step towards Bioavailability Enhancement of Poorly Soluble Drugscitations
- 2023Semi-solid 3D printing of mesoporous silica nanoparticle-incorporated xeno-free nanomaterial hydrogels for protein deliverycitations
- 2023Directing cellular responses in a nanocomposite 3D matrix for tissue regeneration with nanoparticle-mediated drug deliverycitations
- 2022Microfluidic-Assisted Fabrication of Dual-Coated pH-Sensitive Mesoporous Silica Nanoparticles for Protein Deliverycitations
- 2022Core@shell structured ceria@mesoporous silica nanoantibiotics restrain bacterial growth in vitro and in vivocitations
- 2021Stimuli-Responsive, Plasmonic Nanogel for Dual Delivery of Curcumin and Photothermal Therapy for Cancer Treatmentcitations
- 2020Opportunities and Challenges of Silicon‐based Nanoparticles for Drug Delivery and Imagingcitations
- 2019Nanodiamond based complexes for prolonged dexamethasone releasecitations
- 2019Brilliant blue, green, yellow, and red fluorescent diamond particles: synthesis, characterization, and multiplex imaging demonstrationscitations
- 2018Monitoring of the excretion of fluorescent nanocomposites out of the body using artificial neural networkscitations
- 2018Neural Network Classification Method for Solution of the Problem of Monitoring Theremoval of the Theranostics Nanocomposites from an Organismcitations
- 2018A method for optical imaging and monitoring of the excretion of fluorescent nanocomposites from the body using artificial neural networkscitations
- 2013Core–shell designs of photoluminescent nanodiamonds with porous silica coatings for bioimaging and drug delivery I: fabricationcitations
Places of action
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article
Semi-solid 3D printing of mesoporous silica nanoparticle-incorporated xeno-free nanomaterial hydrogels for protein delivery
Abstract
ultifunctional biomaterial inks are in high demand for adapting hydrogels in biomedical applications through three-dimensional (3D) printing. Our previously developed xeno-free system consisting of anionic cellulose nanofibers (T-CNF) and methacrylated galactoglucomannan (GGMMA) as a photo(bio)polymer provides high-performance ink fidelity in extrusion-based 3D printing. The fusion between nanoparticles and this biomaterial-ink system is a promising yet challenging avenue worth exploring, due to the colloidal stability of T-CNF being sensitive to electrostatic interactions. Mesoporous silica nanoparticles (MSNs), with their robust ceramic matrix and fine-tunable surface chemistries, are well-established nanocarriers for different biologicals. Here, we fabricated MSNs with different surface modifications resulting in a net surface charge ranging from highly negative to highly positive to develop printable MSNs-laden nanocomposite biomaterial inks. We utilized rheology as a comprehensive tool to address the matrix interactions with differently surface-charged MSNs. Fluorescently labeled bovine serum albumin (FITC-BSA) was used as a model protein for MSN loading, whereby negatively or neutral-charged MSNs were found suitable to formulate FITC-BSA-loaded biomaterial inks of T-CNF/GGMMA. Depending on the particles’ surface charge, FITC-BSA showed different release profiles and preserved its stability after release. Lastly, the proof-of-concept to deliver large-sized biological cargo with MSN-laden nanocomposite biomaterial inks was established via the 3D printing technique.