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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Simon, Frank
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (15/15 displayed)
- 2023Antimicrobial Brushes on Titanium via “Grafting to” Using Phosphonic Acid/Pyridinium Containing Block Copolymerscitations
- 2023Mineral-impregnated carbon-fiber based reinforcing grids as thermal energy harvesters: A proof-of-concept study towards multifunctional building materialscitations
- 2023Screen printable PANI/carbide-derived carbon supercapacitor electrode ink with chitosan bindercitations
- 2021The Localization Behavior of Different CNTs in PC/SAN Blends Containing a Reactive Componentcitations
- 2020Bio-inspired deposition of electrochemically exfoliated graphene layers for electrical resistance heating applicationscitations
- 2019Elucidating the Chemistry behind the Reduction of Graphene Oxide Using a Green Approach with Polydopaminecitations
- 2018Electrolytic surface treatment for improved adhesion between carbon fibre and polycarbonatecitations
- 2018Electrolytic surface treatment for improved adhesion between carbon fibre and polycarbonate
- 2016Structure-property relations in semifluorinated poly(methacrylate)scitations
- 2016Gold aerogels: Three-dimensional assembly of nanoparticles and their use as electrocatalytic interfacescitations
- 2015Polyelectrolytes to promote adhesive bonds of laser-structured aluminiumcitations
- 2013Poly(lactic acid) composites with poly(lactic acid)-modified carbon nanotubescitations
- 2010Studying the influence of chemical structure on the surface properties of polymer filmscitations
- 2010Poly(2-(dimethylamino)ethyl methacrylate) brushes with incorporated nanoparticles as a SERS active sensing layercitations
- 2007Multiwalled Carbon Nanotubes Produced by a Continuous CVD Method and Their Use in Melt Mixed Composites with Polycarbonate
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article
Antimicrobial Brushes on Titanium via “Grafting to” Using Phosphonic Acid/Pyridinium Containing Block Copolymers
Abstract
<p>Coating medical implants with antibacterial polymers may prevent postoperative infections which are a common issue for conventional titanium implants and can even lead to implant failure. Easily applicable diblock copolymers are presented that form polymer brushes via “grafting to” mechanism on titanium and equip the modified material with antibacterial properties. The polymers carry quaternized pyridinium units to combat bacteria and phosphonic acid groups which allow the linear chains to be anchored to metal surfaces in a convenient coating process. The polymers are synthesized via reversible-addition-fragmentation-chain-transfer (RAFT) polymerization and postmodifications and are characterized using NMR spectroscopy and SEC. Low grafting densities are a major drawback of the “grafting to” approach compared to “grafting from”. Thus, the number of phosphonic acid groups in the anchor block are varied to investigate and optimize the surface binding. Modified titanium surfaces are examined regarding their composition, wetting behavior, streaming potential, and coating stability. Evaluation of the antimicrobial properties revealed reduced bacterial adhesion and biofilm formation for certain polymers, albeit the cell biocompatibility against human gingival fibroblasts is also impaired. The presented findings show the potential of easy-to-apply polymer coatings and aid in designing next-generation implant surface modifications.</p>