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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Ionov, Leonid
University of Bayreuth
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2024Composite Alginate Dialdehyde-Gelatin (ADA-GEL) Hydrogel Containing Short Ribbon-Shaped Fillers for Skeletal Muscle Tissue Biofabricationcitations
- 20244D-Printable Photocrosslinkable Polyurethane-Based Inks for Tissue Scaffold and Actuator Applicationscitations
- 20234D Biofabrication of Mechanically Stable Tubular Constructs Using Shape Morphing Porous Bilayers for Vascularization Applicationcitations
- 20234D‐Printable Photocrosslinkable Polyurethane‐Based Inks for Tissue Scaffold and Actuator Applicationscitations
- 20234D Biofabrication of T‐Shaped Vascular Bifurcationcitations
- 2023Reversibly Photoswitchable High‐Aspect Ratio Surfacescitations
- 2022Fibrous Scaffolds for Muscle Tissue Engineering Based on Touch-Spun Poly(Ester-Urethane) Elastomercitations
- 20204D Biofabrication of fibrous artificial nerve graft for neuron regenerationcitations
- 2017Separator for lithium-sulfur battery based on polymer blend membranecitations
- 2015Reversible thermosensitive biodegradable polymeric actuators based on confined crystallization
- 2014In-situ ATR-FTIR for characterization of thin biorelated polymer filmscitations
- 2012Biomimetic 3D self-assembling biomicroconstructs by spontaneous deformation of thin polymer filmscitations
- 2011Soft microorigami : self-folding polymer filmscitations
- 2005Synthese und Charakterisierung von Polymerbürsten-Oberflächen mit Gradienten und Strukturierung (Synthesis and characterization of patterned and gradient polymer brush surfaces)
Places of action
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article
4D Biofabrication of Mechanically Stable Tubular Constructs Using Shape Morphing Porous Bilayers for Vascularization Application
Abstract
<jats:title>Abstract</jats:title><jats:p>This study reports the fabrication of highly porous electrospun self‐folding bilayers, which fold into tubular structures with excellent mechanical stability, allowing them to be easily manipulated and handled. Two kinds of bilayers based on biocompatible and biodegradable soft (PCL, polycaprolactone) and hard (PHB, poly‐hydroxybutyrate) thermoplastic polymers have been fabricated and compared. Multi‐scroll structures with tunable diameter are obtained after the shape transformation of the bilayer in aqueous media, where PCL‐based bilayer rolled longitudinally and PHB‐based one rolled transversely with respect to the fiber direction. A combination of higher elastic modulus and transverse orientation of fibers with respect to rolling direction allowed precise temporal control of shape transformation of PHB‐bilayer – stress produced by swollen methacrylated hyaluronic acid (HA‐MA) do not relax with time and folding is not affected by the fact that bilayer is fixed in unfolded state in cell culture medium for more than 1 h. This property of PHB‐bilayer allowed cell culturing without a negative effect on its shape transformation ability. Moreover, PHB‐based tubular structure demonstrated superior mechanical stability compared to PCL‐based ones and do not collapse during manipulations that happened to PCL‐based one. Additionally, PHB/HA‐MA bilayers showed superior biocompatibility, degradability, and long‐term stability compared to PCL/HA‐MA.</jats:p>