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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Mahalingam, S.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2022TLR-mediated aggresome-like induced structures comprise antimicrobial peptides and attenuate intracellular bacterial survival
- 2020Generation of Core-Sheath Polymer Nanofibers by Pressurised Gyration.
- 2020Microstructure of fibres pressure-spun from polyacrylonitrile – graphene oxide composite mixtures
- 2020Current methodologies and approaches for the formation of core–sheath polymer fibers for biomedical applications
- 2017New Generation of Tunable Bioactive Shape Memory Mats Integrated with Genetically Engineered Proteins
- 2016Beads, beaded-fibres and fibres: Tailoring the morphology of poly(caprolactone) using pressurised gyration
- 2016New Generation of Tunable Bioactive Shape Memory Mats Integrated with Genetically Engineered Proteins. citations
- 2015Bioinspired electrohydrodynamic ceramic patterning of curved metallic substrates
- 2015Structural, Morphological, and Electron Transport Studies of Annealing Dependent In2O3 Dye-Sensitized Solar Cellcitations
- 2013Micro-scale cantilever testing of linear elastic and elastic-plastic materialscitations
- 2013The Role of Grain Size on Deformation of 316H Austenitic Stainless Steel
- 2013The ductile-brittle transition for nominally pure polycrystalline nickelcitations
- 2008Electrohydrodynamic processing and characterisation of titanium dioxide films.
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article
New Generation of Tunable Bioactive Shape Memory Mats Integrated with Genetically Engineered Proteins.
Abstract
Aligned poly(l-lactide)/poly(methyl methacrylate) binary blend fibers and mats loaded with a chimeric green fluorescence protein having a bioactive peptide with hydroxyapatite binding and mineralization property are prepared by pressurized gyration. The effect of processing parameters on the product morphologies, and the shape memory properties of these samples are investigated. Integration of hydroxyapatite nanoparticles into the fiber assembly is self-directed using the hydroxyapatite-binding property of the peptide genetically engineered to green fluorescence protein. Fluorescence microscopy analysis corroborated with Fourier transform infrared spectroscopy (FTIR) data confirms the integration of the chimeric protein with the fibers. An enzyme based remineralization assay is conducted to study the effects of peptide-mediated mineralization within the fiber mats. Raman and FTIR spectral changes observed following the peptide-mediated mineralization provides an initial step toward a soft-hard material transition. These results show that programmable shape memory properties can be obtained by incorporating genetically engineered bioactive peptide domains into polymer fibers.