| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Gengenbach, Thomas
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (15/15 displayed)
- 2024Interpretation of Complex X-ray Photoelectron Peak Shapes Part II: Case Study of Fe 2p3/2 fitting applied to Austenitic Stainless Steels 316 and 304.citations
- 2020Covalent sizing surface modification as a route to improved interfacial adhesion in carbon fiber-epoxy compositescitations
- 2020Investigating the real-time dissolution of a compositionally complex alloy using inline ICP and correlation with XPScitations
- 2020Real-time dissolution of a compositionally complex alloy using inline ICP and correlation with XPScitations
- 2020Improving the Stability of Ambient-Processed SnO2-Based, Perovskite Solar Cells by UV-Treatment of the Sub-Cellscitations
- 2020Improving the Stability of Ambient processed, SnO2-Based, Perovskite Solar Cells by the UV-treatment of Sub-Cellscitations
- 2019Electrocatalytic CO2 reduction to formate on Cu based surface alloys with enhanced selectivitycitations
- 2019Fiber with Butterfly Wings: Creating Colored Carbon Fibers with Increased Strength, Adhesion, and Reversible Malleabilitycitations
- 2018Morphology and surface properties of high strength siloxane poly(urethane-urea)s developed for heart valve applicationcitations
- 2017Limitations with solvent exchange methods for synthesis of colloidalfullerenescitations
- 2017Reduction of surface fat formation on spray-dried milk powders through emulsion stabilization with λ-carrageenancitations
- 2016Effect of the deformability of guest particles on the tensile strength of tablets from interactive mixturescitations
- 2014Water-dispersible magnetic carbon nanotubes as T2-weighted MRI contrast agentscitations
- 2012One step multifunctional micropatterning of surfaces using asymmetric glow discharge plasma polymerisation
- 2011Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approachcitations
Places of action
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article
Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach
Abstract
The aim of this study is to investigate the changes in physical and chemical surface properties of a fine lactose powder, which has been processed by a mechanical dry coating approach. A commercially available milled lactose monohydrate powder (median diameter around 20 I?m) was dry coated with a pharmaceutical lubricant, magnesium stearate (MgSt). Substantial changes in bulk behavior have been shown previously and the purpose of the current work was to understand the relationship between these bulk changes and physico-chemical changes in the surface. X-ray photoelectron spectroscopy and time-of-flight secondary ion mass spectrometry results demonstrated both qualitatively and quantitatively how the chemical properties of the lactose particle surfaces had been altered. The characterization results indicated that a high-level coverage of a thin coating layer of MgSt has been created through the coating. Inverse gas chromatography was used to probe the surface energetic changes, and at conditions of finite dilution, provided a new insight into surface energy changes. This work demonstrated that the modifications of the surface physical and chemical properties correlated with the reduction in powder cohesion and improvement in powder flow.