| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Zhou, Qi
KTH Royal Institute of Technology
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2023Elucidating Structure Formation in Highly Oriented Triple Cation Perovskite Filmscitations
- 2023Electrical current modulation in wood electrochemical transistorcitations
- 2023Electrical current modulation in wood electrochemical transistorcitations
- 2023Revealing the effect of medium-range structure on silicate glass hardnesscitations
- 2023In Situ Lignin Sulfonation for Highly Conductive Wood/Polypyrrole Porous Compositescitations
- 2022Utilizing native lignin as redox-active material in conductive wood for electronic and energy storage applicationscitations
- 2016Review of the recent developments in cellulose nanocomposite processingcitations
- 2016Investigation of the changes in aerosolization behavior between the jet-milled and spray-dried colistin powders through surface energy characterizationcitations
- 2015Core-shell cellulose nanofibers for biocomposites - Nanostructural effects in hydrated statecitations
- 2014Surface modification of cellulose nanocrystals by grafting with poly(lactic acid)citations
- 2013Nanocomposites of bacterial cellulose nanofibers and chitin nanocrystalscitations
- 2013Effect of surface coating with magnesium stearate via mechanical dry powder coating approach on the aerosol performance of micronized drug powders from dry powder inhalerscitations
- 2011Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approachcitations
- 2009Nanostructured biocomposites based on bacterial cellulosic nanofibers compartmentalized by a soft hydroxyethylcellulose matrix coatingcitations
Places of action
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article
Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach
Abstract
The aim of this study is to investigate the changes in physical and chemical surface properties of a fine lactose powder, which has been processed by a mechanical dry coating approach. A commercially available milled lactose monohydrate powder (median diameter around 20 I?m) was dry coated with a pharmaceutical lubricant, magnesium stearate (MgSt). Substantial changes in bulk behavior have been shown previously and the purpose of the current work was to understand the relationship between these bulk changes and physico-chemical changes in the surface. X-ray photoelectron spectroscopy and time-of-flight secondary ion mass spectrometry results demonstrated both qualitatively and quantitatively how the chemical properties of the lactose particle surfaces had been altered. The characterization results indicated that a high-level coverage of a thin coating layer of MgSt has been created through the coating. Inverse gas chromatography was used to probe the surface energetic changes, and at conditions of finite dilution, provided a new insight into surface energy changes. This work demonstrated that the modifications of the surface physical and chemical properties correlated with the reduction in powder cohesion and improvement in powder flow.