| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Ito, Keita
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2023Warp-knitted fabric structures for a novel biomimetic artificial intervertebral disc for the cervical spine
- 2022Surface texture analysis of different focal knee resurfacing implants after 6 and 12 months in vivo in a goat modelcitations
- 2022Surface texture analysis of different focal knee resurfacing implants after 6 and 12 months in vivo in a goat modelcitations
- 2022A bovine nucleus pulposus explant culture modelcitations
- 2021Proteoglycan 4 reduces friction more than other synovial fluid components for both cartilage-cartilage and cartilage-metal articulationcitations
- 2020Accuracy of beam theory for estimating bone tissue modulus and yield stress from 3-point bending tests on rat femoracitations
- 2020T2* mapping in an equine articular groove model - visualizing changes in collagen orientationcitations
- 2019Bi-layered micro-fibre reinforced hydrogels for articular cartilage regenerationcitations
- 2019Resorption of the calcium phosphate layer on S53P4 bioactive glass by osteoclastscitations
- 2017Magnetic domain walls in nanostrips of single-crystalline Fe4N thin films with fourfold in-plane magnetic anisotropycitations
- 2016Mechanical properties of bioactive glass putty formulations
- 2016Silk fibroin as biomaterial for bone tissue engineeringcitations
- 2013A new model to study healing of a complex femur fracture with concurrent soft tissue injury in sheepcitations
Places of action
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article
T2* mapping in an equine articular groove model - visualizing changes in collagen orientation
Abstract
<p>T2* mapping is promising for the evaluation of articular cartilage collagen. In this work, a groove model in a large animal is used as a model for post-traumatic arthritis. We hypothesized that T2* mapping could be employed to differentiate between healthy and (subtly) damaged cartilage. Eight carpal joints were obtained from four adult Shetland ponies that had been included in the groove study. In this model, grooves were surgically created on the proximal articular surface of the intermediate carpal bone (radiocarpal joint) and the radial facet of the third carpal bone (middle carpal joint) by either coarse disruption or sharp incision. After nine months, T2* mapping of the entire carpal joint was carried out on a 7.0T whole body magnetic resonance imaging (MRI) scanner by means of a gradient echo multi echo sequence. Afterwards, assessment of collagen orientation was carried out based on Picrosirius Red-stained histological sections, visualized by polarized light microscopy (PLM). The average T2* relaxation time in grooved samples was lower than in contralateral control sites. Opposite to the grooved areas, the "kissing sites" had a higher average T2* relaxation time than the grooved sites. PLM showed mild changes in orientation of the collagen fibers, particularly around blunt grooves. This work shows that T2* relaxation times are different in healthy cartilage versus (early) damaged cartilage, as induced by the equine groove model. Additionally, the average T2* relaxation times are different in kissing lesions versus the grooved sites. This article is protected by copyright. All rights reserved.</p>