| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Krause, Matthias
Helmholtz-Zentrum Dresden-Rossendorf
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (16/16 displayed)
- 2024Exceptional high-temperature in-air stable solar absorber coatings based on aluminium titanium oxynitride nanocomposites
- 2023Exceptionally high-temperature in-air stability of transparent conductive oxide tantalum-doped tin dioxidecitations
- 2023Advanced characterization and optical simulation for the design of solar selective coatings based on carbon: transition metal carbide nanocomposites
- 2023Design of high-temperature solar-selective coatings based on aluminium titanium oxynitrides AlyTi1−y(OxN1−x). Part 1: Advanced microstructural characterization and optical simulation
- 2023Solar selective coatings based on Carbon:Transition Metal Nanocomposites
- 2022Triboscopic Investigation of Self-Mated Carbon Coatings in Non-Lubricated Friction Conditions
- 2022Low-Friction of ta-C Coatings Paired with Brass and Other Materials under Vacuum and Atmospheric Conditionscitations
- 2021Comprehensive microstructural and optical characterization of the thermal stability of aluminum‑titanium oxynitride thin films after high temperature annealing in air
- 2021Tailoring Crystalline Structure of Titanium Oxide Films for Optical Applications Using Non-Biased Filtered Cathodic Vacuum Arc Deposition at Room Temperature
- 2021Impact of low energy ion beams on the properties of rr-P3HT films
- 2021Comprehensive microstructural and optical characterization of the thermal stability of aluminum-titanium oxynitride thin films after high temperature annealing in air
- 2020On the effect of thin film growth mechanisms on the specular reflectance of aluminum thin films deposited via filtered cathodic vacuum arc
- 2020Long‐Term Immobilization in Elderly Females Causes a Specific Pattern of Cortical Bone and Osteocyte Deterioration Different From Postmenopausal Osteoporosiscitations
- 2020Directionality of metal-induced crystallization and layer exchange in amorphous carbon/nickel thin film stackscitations
- 2016Thermally induced formation of metastable nanocomposites in amorphous Cr-Zr-O thin films deposited using reactive ion beam sputteringcitations
- 2016Carbon : nickel nanocomposite templates - predefined stable catalysts for diameter-controlled growth of single-walled carbon nanotubescitations
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article
Long‐Term Immobilization in Elderly Females Causes a Specific Pattern of Cortical Bone and Osteocyte Deterioration Different From Postmenopausal Osteoporosis
Abstract
<jats:title>ABSTRACT</jats:title><jats:p>Immobilization as a result of long‐term bed rest can lead to gradual bone loss. Because of their distribution throughout the bone matrix and remarkable interconnectivity, osteocytes represent the major mechanosensors in bone and translate mechanical into biochemical signals controlling bone remodeling. To test whether immobilization affects the characteristics of the osteocyte network in human cortical bone, femoral diaphyseal bone specimens were analyzed in immobilized female individuals and compared with age‐matched postmenopausal individuals with primary osteoporosis. Premenopausal and postmenopausal healthy individuals served as control groups. Cortical porosity, osteocyte number and lacunar area, the frequency of hypermineralized lacunae, as well as cortical bone calcium content (CaMean) were assessed using bone histomorphometry and quantitative backscattered electron imaging (qBEI). Bone matrix properties were further analyzed by Fourier transform infrared spectroscopy (FTIR). In the immobilization group, cortical porosity was significantly higher, and qBEI revealed a trend toward higher matrix mineralization compared with osteoporotic individuals. Osteocyte density and canalicular density showed a declining rate from premenopausal toward healthy postmenopausal and osteoporotic individuals with peculiar reductions in the immobilization group, whereas the number of hypermineralized lacunae accumulated inversely. In conclusion, reduced osteocyte density and impaired connectivity during immobilization are associated with a specific bone loss pattern, reflecting a phenotype clearly distinguishable from postmenopausal osteoporosis. Immobilization periods may lead to a loss of survival signals for osteocytes, provoking bone loss that is even higher than in osteoporosis states, whereas osteocytic osteolysis remains absent. © 2020 The Authors. <jats:italic>Journal of Bone and Mineral Research</jats:italic> published by American Society for Bone and Mineral Research.</jats:p>