| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Ding, Ming
University of Southern Denmark
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (12/12 displayed)
- 2020Strontium ion reinforced bioceramic scaffold for load bearing bone regenerationcitations
- 2018Calcium phosphate precipitation in experimental gaps between fluoride-containing fast-setting calcium silicate cement and dentincitations
- 2016Demineralized bone matrix and human cancellous bone enhance fixation of porous-coated titanium implants in sheepcitations
- 2015A reversal phase arrest uncoupling the bone formation and resorption contributes to the bone loss in glucocorticoid treated ovariectomised aged sheepcitations
- 2013Single-mode tunable laser emission in the single-exciton regime from colloidal nanocrystalscitations
- 2013Evaluating of bone healing around porous coated titanium implant and potential systematic bias on the traditional sampling methodcitations
- 2012Chalcogenide microsphere fabricated from fiber tapers using contact with a high-temperature ceramic surfacecitations
- 2012The effects of bone marrow aspirate, bone graft, and collagen composites on fixation of titanium implantscitations
- 2011Bioreactor activated graft material for early implant fixation in bone
- 2011A compact broadband microfiber Bragg gratingcitations
- 2010Demineralized bone matrix and human cancellous bone enhance fixation of titanium implants
- 2007The effect of bone marrow aspirate, bone graft and collagen composites on fixation of bone implants
Places of action
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article
The effects of bone marrow aspirate, bone graft, and collagen composites on fixation of titanium implants
Abstract
Replacement of extensive local bone loss especially in revision joint arthroplasty and spine fusion is a significant clinical challenge. Allograft and autograft have been considered as gold standards for bone replacement. However, there are several disadvantages such as donor site pain, bacterial contamination, and non union as well as the potential risk of disease transmission. Hydroxyapatite and collagen composites (HA/Collagen) have the potential in mimicking and replacing skeletal bones. This study attempted to determine the effects of newly developed HA/Collagen-composites with and without bone marrow aspirate (BMA) on enhancement of bone implant fixation. Method: Titanium alloy implants were inserted into bilateral femoral condyles of eight skeletally mature sheep, four implants per sheep. The implant had a circumferential gap of 2 mm. The gap was filled with: HA/Collagen; HA/Collagen-BMA; autograft or allograft. Allograft was served as the control group. The observation period was 5 weeks. The sheep were euthanized and both femurs were harvested. A push-out mechanical test and histological analysis were performed. Results: No significant differences were seen in the mechanical properties and histomorphometry between autograft and allograft groups. The implants in both the HA/Collagen and HA/Collagen-BMA groups were mostly surrounded by fibrous tissue. Thus, mechanical testing of these samples was impossible. The histomorphometry results showed significantly more new bone and bone ongrowth in the allograft and autograft group compared with the HA/Collagen and HA/Collagen-BMA groups, but no significant difference between HA/Collagen and HA/Collagen-BMA. Conclusion: Autograft and allograft have similar effect on fixation of bone implants. HA/Collagen composite with or without BMA has no effect on the early fixation of bone implants in this sheep model. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012.