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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Drouet, Christophe
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (23/23 displayed)
- 2023Biomaterial strategies to combat implant infections: new perspectives to old challengescitations
- 2023Biocompatible MgFeCO3 Layered Double Hydroxide (LDH) for Bone Regeneration—Low-Temperature Processing through Cold Sintering and Freeze-Castingcitations
- 2022Influence of flax fibers on epoxide-amine composites: Energetics of interphase formationcitations
- 2021Further insight on amine-metal reaction in epoxy systemscitations
- 2021Activated Carbon Fiber Cloth/Biomimetic Apatite: A Dual Drug Delivery Systemcitations
- 2021Activated Carbon Fiber Cloth/Biomimetic Apatite: A Dual Drug Delivery Systemcitations
- 2020Direct evidence of amine-metal reaction in epoxy systems: An in situ calorimetry study of the interphase formationcitations
- 2020Influence of carbonation on the low-temperature consolidation by Spark Plasma Sintering of carbonated calcium phosphate bioceramicscitations
- 2020First successful stabilization of consolidated amorphous calcium phosphate (ACP) by cold sintering: toward highly-resorbable reactive bioceramicscitations
- 2018Consolidation of bone-like apatite bioceramics by spark plasma sintering of amorphous carbonated calcium phosphate at very low temperaturecitations
- 2017Types of ceramics: Material classcitations
- 2017Types of ceramics : material class
- 2015Biomimetic apatite-based composite materials obtained by spark plasma sintering (SPS): physicochemical and mechanical characterizationscitations
- 2014Peroxide-doped apatites: Preparation and effect of synthesis parameterscitations
- 2012Shaping of nanostructured materials or coatings through Spark Plasma Sinteringcitations
- 2012Hydroxyapatite coating on titanium by a low energy plasma spraying mini-guncitations
- 2010Biomimetic apatite sintered at very low temperature by spark plasma sintering: Physico-chemistry and microstructure aspectscitations
- 2010Medical potentialities of biomimetic apatites through adsorption, ionic substitution, and mineral/organic associations: three illustrative examplescitations
- 2009Nanocrystalline apatites: From powders to biomaterialscitations
- 2009Low temperature consolidation of nanocrystalline apatites. Toward a new generation of calcium phosphate ceramics
- 2009Adsorption and release of BMP-2 on nanocrystalline apatite-coated and uncoated hydroxyapatite/beta-tricalcium phosphate porous ceramics.citations
- 2009Adsorption and release of BMP-2 on nanocrystalline apatite-coated and uncoated hydroxyapatite/b-tricalcium phosphate porous ceramicscitations
- 2006Bioceramics: spark plasma sintering (SPS) of calcium phosphatescitations
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article
Adsorption and release of BMP-2 on nanocrystalline apatite-coated and uncoated hydroxyapatite/beta-tricalcium phosphate porous ceramics.
Abstract
The association of bone morphogenetic proteins (BMPs) with calcium phosphate bioceramics is known to confer them osteoinductive properties. The aim of this study was to evaluate the surface properties, especially regarding recombinant human BMP-2 (rhBMP-2) adsorption and release, of commercial sintered biphasic calcium phosphate ceramics after coating with biomimetic nanocrystalline apatite. The raw and coated ceramics exhibited similar macroporous structures but different nanometer-sized pores contents. Both types of ceramics showed Langmuir-type adsorption isotherms of rhBMP-2. The coating noticeably increased the rate of adsorption and the total amount of growth factor taken up, but the maximum coverage per surface area unit as well as the affinity constant appeared lower for coated ceramics compared with raw ceramic surfaces. The limited advantage gained by coating the ceramics can be assigned to a lower accessibility of the surface adsorption sites compared with the raw ceramics. The quantity of rhBMP-2 spontaneously released in cell culture medium during the first weeks was lower for coated samples than for uncoated ceramics and represented a minor fraction of the total adsorbed amount. In conclusion, the nanocrystalline apatite coating was found to favor the adsorption of rhBMP-2 while providing a mean to fine tune the release of the growth factor. (c) 2009 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2009.