| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Echeverry-Rendon, Monica
IMDEA Materials
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (10/10 displayed)
- 2024Cytocompatibility, cell‐material interaction, and osteogenic differentiation of MC3T3‐E1 pre‐osteoblasts in contact with engineered Mg/PLA compositescitations
- 2020Effect of surface characteristics on the antibacterial properties of titanium dioxide nanotubes produced in aqueous electrolytes with carboxymethyl cellulose.citations
- 2019Considerations about sterilization of samples of pure magnesium modified by plasma electrolytic oxidationcitations
- 2019Coatings for biodegradable magnesium-based supports for therapy of vascular diseasecitations
- 2018Formation of nanotubular TiO2 structures with varied surface characteristics for biomaterial applicationscitations
- 2018Improved corrosion resistance of commercially pure magnesium after its modification by plasma electrolytic oxidation with organic additivescitations
- 2018Novel coatings obtained by plasma electrolytic oxidation to improve the corrosion resistance of magnesium-based biodegradable implantscitations
- 2018Balancing biofunctional and biomechanical properties using porous titanium reinforced by carbon nanotubes.citations
- 2017Modification of titanium alloys surface properties by plasma electrolytic oxidation (PEO) and influence on biological response.citations
- 2015Osseointegration improvement by plasma electrolytic oxidation of modified titanium alloys surfaces.citations
Places of action
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article
Cytocompatibility, cell‐material interaction, and osteogenic differentiation of MC3T3‐E1 pre‐osteoblasts in contact with engineered Mg/PLA composites
Abstract
<jats:title>Abstract</jats:title><jats:p>Bioabsorbable Mg wire‐reinforced poly‐lactic acid (PLA) matrix composites are potential candidate for load‐bearing orthopedic implants offering tailorable mechanical and degradation properties by stacking sequence, volume fraction and surface modification of Mg wires. In this study, we investigated the cytocompatibility, cell‐material interaction, and bone differentiation behavior of MC3T3‐E1 pre‐osteoblast cells for medical‐grade PLA, Mg/PLA, and PEO‐Mg/PLA (having PEO surface modification on Mg wires) composites. MTT and live/dead assay showed excellent biocompatibility of both composites while cell‐material interaction analysis revealed that cells were able to adhere and proliferate on the surface of composites. Cells on the longitudinal surface of composites showed a high and uniform cell density while those on transversal surfaces initially avoided Mg regions but later migrated back after the formation of the passivation layer. Bone differentiation tests showed that cells in extracts of PLA and composites were able to initiate the differentiation process as osteogenesis‐related gene expressions, alkaline phosphatase protein quantity, and calcium mineralization increased after 7 and 14 days of culture. Interestingly, the bone differentiation response of PEO‐Mg/PLA composite was found to be similar to medical‐grade PLA, proving its superiority over Mg/PLA composite.</jats:p>