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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Herazo, Cristina Isabel Castro
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (15/15 displayed)
- 2023Isolation of cellulose microfibers and nanofibers by mechanical fibrillation in a water-free solventcitations
- 2023The Evolution and Future Trends of Unsaturated Polyester Biocompositescitations
- 2021Phase distribution changes of neat unsaturated polyester resin and their effects on both thermal stability and dynamic-mechanical propertiescitations
- 2019Development of novel three-dimensional scaffolds based on bacterial nanocellulose for tissue engineering and regenerative medicinecitations
- 2017Physical Characterization of Bacterial Cellulose Produced by Komagataeibacter medellinensis Using Food Supply Chain Waste and Agricultural By-Products as Alternative Low-Cost Feedstockscitations
- 2017Influence of tribological test on the global conversion of natural compositescitations
- 2017Effect of molecular weight reduction by60Co irradiation and polymer concentration in chitosan coating surface properties in relation to the surface properties of red tilapia (oreochromis spp.)
- 2015Highly percolated poly(vinyl alcohol) and bacterial nanocellulose synthesized in situ by physical-crosslinkingcitations
- 2014Wettability of gelatin coating formulations containing cellulose nanofibers on banana and eggplant epicarpscitations
- 2014In situ production of nanocomposites of poly(vinyl alcohol) and cellulose nanofibrils from Gluconacetobacter bacteriacitations
- 2014Synthesis of thermoplastic starch-bacterial cellulose nanocomposites via in situ fermentationcitations
- 2013Bacterial cellulose nanocomposites developed by in-situ fermentation
- 2012Biodegradability of Banana and Plantain Cellulose Microfibrils Films in Anaerobic Conditionscitations
- 2012Surface free energy of films of alkali-treated cellulose microfibrils from banana rachiscitations
- 2007Determinación de condiciones óptimas para el tratamiento alcalino de fibras de fique empleadas como reforzantes de materiales compuestos
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article
Development of novel three-dimensional scaffolds based on bacterial nanocellulose for tissue engineering and regenerative medicine
Abstract
<p>Despite the efforts focused on manufacturing biological engineering scaffolds for tissue engineering and regenerative medicine, a biomaterial that meets the necessary characteristics for these applications has not been developed to date. Bacterial nanocellulose (BNC) is an outstanding biomaterial for tissue engineering and regenerative medicine; however, BNC's applications have been focused on two-dimensional (2D) medical devices, such as wound dressings. Given the need for three-dimensional (3D) porous biomaterials, this work evaluates two methods to generate (3D) BNC scaffolds. The structural characteristics and physicochemical, mechanical, and cell behaviour properties were evaluated. Likewise, the effects of the pore size and surface area in the mechanical performance of BNC biomaterials and their cell response in a fibroblast cell line are discussed for the first time. In this study, a new method is proposed for the development of 3D BNC scaffolds using paraffin wax. This new method is less time-consuming, more robust in removing the paraffin and less aggressive toward the BNC microstructure. Moreover, the biomaterial had regular porosity with good mechanical behaviour; the cells can adhere and increase in number without overcrowding. Regarding the pore size and surface area, highly interconnected porosities (measuring approximately 60 μm) and high surface area are advantageous for the biomaterial's mechanical properties and cell behaviour.</p>