Materials Map

Discover the materials research landscape. Find experts, partners, networks.

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The Materials Map is an open tool for improving networking and interdisciplinary exchange within materials research. It enables cross-database search for cooperation and network partners and discovering of the research landscape.

The dashboard provides detailed information about the selected scientist, e.g. publications. The dashboard can be filtered and shows the relationship to co-authors in different diagrams. In addition, a link is provided to find contact information.

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The Materials Map is still under development. In its current state, it is only based on one single data source and, thus, incomplete and contains duplicates. We are working on incorporating new open data sources like ORCID to improve the quality and the timeliness of our data. We will update Materials Map as soon as possible and kindly ask for your patience.

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Naji, M.
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Fernandes, Mh

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in Cooperation with on an Cooperation-Score of 37%

Topics

Publications (25/25 displayed)

  • 2023Titanium dioxide nanoparticles affect osteoblast-derived exosome cargos and impair osteogenic differentiation of human mesenchymal stem cells15citations
  • 2023Full physicochemical and biocompatibility characterization of a supercritical CO2 sterilized nano-hydroxyapatite/chitosan biodegradable scaffold for periodontal bone regeneration25citations
  • 2022Fabrication of a biodegradable and cytocompatible magnesium/ nanohydroxyapatite/fluorapatite composite by upward friction stir processing for biomedical applications32citations
  • 202145S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Method6citations
  • 2020Femtosecond laser microstructuring of alumina toughened zirconia for surface functionalization of dental implants72citations
  • 2019Influence of PLLA/PCL/HA Scaffold Fiber Orientation on Mechanical Properties and Osteoblast Behavior25citations
  • 2019Inhibitory Effect of 5-Aminoimidazole-4-Carbohydrazonamides Derivatives Against Candida spp. Biofilm on Nanohydroxyapatite Substrate7citations
  • 2018Processing, characterization, and in vivo evaluation of poly (L-lactic acid)-fish gelatin electrospun membranes for biomedical applications4citations
  • 2018Femtosecond laser impact on calcium phosphate bioceramics assessed by micro-Raman spectroscopy and osteoblastic behaviour9citations
  • 2018Development of bioactive tellurite-lanthanide ions-reinforced hydroxyapatite composites for biomedical and luminescence applications2citations
  • 2018Highly porous 45S5 bioglass-derived glass-ceramic scaffolds by gelcasting of foams15citations
  • 2018Micropatterned Silica Films with Nanohydroxyapatite for Y-TZP Implants4citations
  • 2017Incorporation of glass-reinforced hydroxyapatite microparticles into poly(lactic acid) electrospun fibre mats for biomedical applications22citations
  • 2016Biodegradation, biocompatibility, and osteoconduction evaluation of collagen-nanohydroxyapatite cryogels for bone tissue regeneration59citations
  • 2016Effect of Sterilization Methods on Electrospun Poly(lactic acid) (PLA) Fiber Alignment for Biomedical Applications195citations
  • 2015Smart electroconductive bioactive ceramics to promote in situ electrostimulation of bone24citations
  • 2015Novel cerium doped glass-reinforced hydroxyapatite with antibacterial and osteoconductive properties for bone tissue regeneration54citations
  • 2014Modulation of human dermal microvascular endothelial cell and human gingival fibroblast behavior by micropatterned silica coating surfaces for zirconia dental implant applications34citations
  • 2014Processing strategies for smart electroconductive carbon nanotube-based bioceramic bone grafts6citations
  • 2013Development and characterization of lanthanides doped hydroxyapatite composites for bone tissue application21citations
  • 2012Development and Characterization of Ag2O-Doped ZnLB Glasses and Biological Assessment of Ag2O-ZnLB-Hydroxyapatite Composites11citations
  • 2010Evaluation of human osteoblastic cell response to plasma-sprayed silicon-substituted hydroxyapatite coatings over titanium substrates54citations
  • 2010New titanium and titanium/hydroxyapatite coatings on ultra-high-molecular-weight polyethylene-in vitro osteoblastic performance8citations
  • 2009Assessment of the osteoblastic cell response to a zinc glass reinforced hydroxyapatite composite (Zn-GRHA)1citations
  • 2005In vitro studies of calcium phosphate glass ceramics with different solubility with the use of human bone marrow cells15citations

Places of action

Chart of shared publication
Piperni, Sg
1 / 1 shared
De Souza, W.
1 / 1 shared
Melo, Sa
1 / 1 shared
Granjeiro, Jm
1 / 1 shared
Ribeiro, Ar
1 / 3 shared
Rocha, La
1 / 2 shared
Dias, Mm
1 / 9 shared
Monteiro, Fj
9 / 15 shared
Manrique, Ya
1 / 2 shared
Salgado, Cl
2 / 3 shared
Souto Lopes, M.
1 / 1 shared
Santos, Tg
1 / 2 shared
Inacio, Pl
1 / 1 shared
Santos, C.
1 / 8 shared
Alves, P.
1 / 7 shared
Ferreira, Fb
1 / 1 shared
Alves, Mm
1 / 1 shared
Vidal, C.
1 / 2 shared
Carmezim, Mj
1 / 1 shared
Triches, Es
3 / 3 shared
De Siqueira, L.
3 / 3 shared
Daskalova, A.
1 / 6 shared
Trifonov, A.
1 / 3 shared
Buchvarov, I.
1 / 6 shared
Carvalho, A.
3 / 11 shared
Cunha Reis, C.
1 / 1 shared
Sousa, Sr
1 / 2 shared
Ribeiro, N.
1 / 2 shared
Paredes, Mba
1 / 1 shared
Sousa, Jc
1 / 1 shared
Cerqueira, F.
1 / 6 shared
Gabriel, C.
1 / 5 shared
Medeiros, R.
1 / 2 shared
Ferraz, Mp
3 / 6 shared
Dias, Am
1 / 6 shared
Ribeiro, Ai
1 / 4 shared
Proenca, Mf
1 / 1 shared
Caseiro, Ar
1 / 2 shared
Branco, M.
1 / 2 shared
Mauricio, Ac
1 / 5 shared
Gomes, Ps
12 / 14 shared
Pedrosa, Ss
1 / 1 shared
Rema, A.
1 / 1 shared
Amorim, I.
1 / 2 shared
Silva, Dm
3 / 4 shared
Sencadas, V.
3 / 110 shared
Santos, Jd
10 / 37 shared
Branquinho, Mv
1 / 1 shared
Lasgorceix, M.
1 / 5 shared
Monteiro, F.
1 / 5 shared
Hocquet, S.
1 / 2 shared
Ott, C.
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Cambier, F.
1 / 1 shared
Leriche, A.
1 / 2 shared
Boilet, L.
1 / 3 shared
Stamboulis, A.
1 / 6 shared
Nandyala, Sh
3 / 4 shared
Hungerford, G.
1 / 7 shared
Gouveia, Rf
1 / 1 shared
Cesar, Pf
1 / 1 shared
Miranda, Rbp
1 / 1 shared
Correia, Co
1 / 1 shared
Santos, D.
1 / 5 shared
Colaco, Bj
1 / 1 shared
Valente, Tam
1 / 1 shared
Bastos, Ac
1 / 3 shared
Belmonte, M.
1 / 16 shared
Silva, Rf
3 / 10 shared
Mata, D.
2 / 5 shared
Oliveira, Fj
2 / 5 shared
Neto, Ma
1 / 2 shared
Lopes, Ma
9 / 37 shared
Sooraj Hussain, Ns
1 / 2 shared
Morais, Ds
1 / 2 shared
Fernandes, S.
1 / 9 shared
Sampaio, Paula
2 / 7 shared
Costa, E.
1 / 10 shared
Laranjeira, Ms
1 / 1 shared
Santos Silva, A.
1 / 19 shared
Pelaez Vargas, A.
1 / 1 shared
Hansford, D.
1 / 1 shared
Coimbra, S.
1 / 1 shared
Araujo, Rf
1 / 1 shared
Ferreira, Nm
1 / 4 shared
Fernandes, Ajs
1 / 4 shared
Garcia, Mp
1 / 1 shared
Coelho, J.
2 / 16 shared
Nunes, Oc
1 / 4 shared
Pacheco, Ap
1 / 1 shared
Botelho, C.
1 / 1 shared
Vila, M.
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Silva, Ma
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Sooraj Hussain, N.
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Dias, Ag
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Cabral, Att
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Chart of publication period
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Co-Authors (by relevance)

  • Piperni, Sg
  • De Souza, W.
  • Melo, Sa
  • Granjeiro, Jm
  • Ribeiro, Ar
  • Rocha, La
  • Dias, Mm
  • Monteiro, Fj
  • Manrique, Ya
  • Salgado, Cl
  • Souto Lopes, M.
  • Santos, Tg
  • Inacio, Pl
  • Santos, C.
  • Alves, P.
  • Ferreira, Fb
  • Alves, Mm
  • Vidal, C.
  • Carmezim, Mj
  • Triches, Es
  • De Siqueira, L.
  • Daskalova, A.
  • Trifonov, A.
  • Buchvarov, I.
  • Carvalho, A.
  • Cunha Reis, C.
  • Sousa, Sr
  • Ribeiro, N.
  • Paredes, Mba
  • Sousa, Jc
  • Cerqueira, F.
  • Gabriel, C.
  • Medeiros, R.
  • Ferraz, Mp
  • Dias, Am
  • Ribeiro, Ai
  • Proenca, Mf
  • Caseiro, Ar
  • Branco, M.
  • Mauricio, Ac
  • Gomes, Ps
  • Pedrosa, Ss
  • Rema, A.
  • Amorim, I.
  • Silva, Dm
  • Sencadas, V.
  • Santos, Jd
  • Branquinho, Mv
  • Lasgorceix, M.
  • Monteiro, F.
  • Hocquet, S.
  • Ott, C.
  • Cambier, F.
  • Leriche, A.
  • Boilet, L.
  • Stamboulis, A.
  • Nandyala, Sh
  • Hungerford, G.
  • Gouveia, Rf
  • Cesar, Pf
  • Miranda, Rbp
  • Correia, Co
  • Santos, D.
  • Colaco, Bj
  • Valente, Tam
  • Bastos, Ac
  • Belmonte, M.
  • Silva, Rf
  • Mata, D.
  • Oliveira, Fj
  • Neto, Ma
  • Lopes, Ma
  • Sooraj Hussain, Ns
  • Morais, Ds
  • Fernandes, S.
  • Sampaio, Paula
  • Costa, E.
  • Laranjeira, Ms
  • Santos Silva, A.
  • Pelaez Vargas, A.
  • Hansford, D.
  • Coimbra, S.
  • Araujo, Rf
  • Ferreira, Nm
  • Fernandes, Ajs
  • Garcia, Mp
  • Coelho, J.
  • Nunes, Oc
  • Pacheco, Ap
  • Botelho, C.
  • Vila, M.
  • Silva, Ma
  • Sooraj Hussain, N.
  • Dias, Ag
  • Cabral, Att
OrganizationsLocationPeople

article

Biodegradation, biocompatibility, and osteoconduction evaluation of collagen-nanohydroxyapatite cryogels for bone tissue regeneration

  • Colaco, Bj
  • Monteiro, Fj
  • Salgado, Cl
  • Fernandes, Mh
Abstract

Designing biomimetic biomaterials inspired by the natural complex structure of bone and other hard tissues is still a challenge nowadays. The control of the biomineralization process onto biomaterials should be evaluated before clinical application. Aiming at bone regeneration applications, this work evaluated the in vitro biodegradation and interaction between human bone marrow stromal cells (HBMSC) cultured on different collagen/nanohydroxyapatite cryogels. Cell proliferation, differentiation, morphology, and metabolic activity were assessed through different protocols. All the biocomposite materials allowed physiologic apatite deposition after incubation in simulated body fluid and the cryogel with the highest nanoHA content showed to have the highest mechanical strength (DMA). The study clearly showed that the highest concentration of nanoHA granules on the cryogels were able to support cell type's survival, proliferation, and individual functionality in a monoculture system, for 21 days. In fact, the biocomposites were also able to differentiate HBMSCs into osteoblastic phenotype. The composites behavior was also assessed in vivo through subcutaneous and bone implantation in rats to evaluate its tissue-forming ability and degradation rate. The cryogels Coll/nanoHA (30 : 70) promoted tissue regeneration and adverse reactions were not observed on subcutaneous and bone implants. The results achieved suggest that scaffolds of Coll/nanoHA (30 : 70) should be considered promising implants for bone defects that present a grotto like appearance with a relatively small access but a wider hollow inside. This material could adjust to small dimensions and when entering into the defect, it could expand inside and remain in close contact with the defect walls, thus ensuring adequate osteoconductivity. (c) 2015 Wiley Periodicals, Inc.

Topics
  • Deposition
  • impedance spectroscopy
  • morphology
  • strength
  • composite
  • defect
  • forming
  • biomaterials
  • biocompatibility