| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Navarro, M.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (28/28 displayed)
- 2022Evaluation of Fourier Transform Infrared Spectroscopy as a First-Line Typing Tool for the Identification of Extended-Spectrum β-Lactamase-Producing <i>Klebsiella pneumoniae</i> Outbreaks in the Hospital Setting.citations
- 2019Influence of the addition of fibers in different phases of the spinning process on the behaviour of cotton blended yarns
- 2019Influence of the addition of nettle and hemp fibers to cotton based yarns on the moisture management properties
- 2014Role of porosity and pore architecture in the in vivo bone regeneration capacity of biodegradable glass scaffoldscitations
- 2011Electrochemical treatment to condition contaminated EAFD as addition to immobilisation mortar in low level waste concrete containerscitations
- 2010Materials surface effects on biological interactionscitations
- 2008A novel hybrid calcium phosphate/ACP injectable cement
- 2008Of the in vivo behavior of calcium phosphate cements and glasses as bone substitutescitations
- 2008Surface characterization and cell response of a PLA/CaP glass biodegradable composite materialcitations
- 2007Micro and nanostructure evolution study of novel injectable calcium phosphate cements prepared by ceramic and sol-gel processes
- 2006Development of a biodegradable composite scaffold for bone tissue engineeringcitations
- 2006Transparent micro- and nanopatterned poly(lactic acid) for biomedical applicationscitations
- 2005In vivo behavior of calcium phosphate glasses with controlled solubilitycitations
- 2005Surface characterization of completely degradable composite scaffoldscitations
- 2005In vitro degradation behavior of a novel bioresorbable composite material based on PLA and a soluble CaP glasscitations
- 2004Development and cell response of a new biodegradable composite scaffold for guided bone regenerationcitations
- 2004Macroporous calcium phosphate glass ceramic scaffold for bone regeneration
- 2004New macroporous calcium phosphate glass ceramic for guided bone regenerationcitations
- 2004Calcium phosphate bone substitutes.
- 2004Control de la velocidad de degradación de materiales compuestos para aplicacions biomédicas
- 2004Development of a new calcium phosphate glass ceramic porous scaffold for guided bone regenerationcitations
- 2004Control de la velocidad de degradación de materiales compuestos para aplicaciones biomédicas.
- 2003Cellular response to calcium phosphate glasses with controlled solubilitycitations
- 2003Physicochemical degradation of titania-stabilized soluble phosphate glasses for medical applicationscitations
- 2002Improvement of the stability and mechanical properties of resorbable phosphate glasses by the addition of TiO2citations
- 2002Improvement of the stability and mechanical properties of resorbable phosphate glasses by the addition of TIO<inf>2</inf>
- 2001Chemical durability and mechanical properties of calcium phosphate glasses with the addition of Fe<inf>2</inf>O<inf>3</inf>, TiO<inf>2</inf> and ZnO
- 2000Chemical durability and mechanical properties of calcium phosphate glasses with the addition of Fe2O3, TiO2 and ZnO
Places of action
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article
Role of porosity and pore architecture in the in vivo bone regeneration capacity of biodegradable glass scaffolds
Abstract
The aim of this work is to shed light on the role of porosity and pore architecture in the in vivo bone regeneration capacity of biodegradable glass scaffolds. A calcium phosphate glass in the system P2O5-CaO-Na2O-TiO2 was foamed using two different porogens, namely albumen and hydrogen peroxide (H2O2); the resulting three-dimensional porous structures were characterized and implanted in New Zealand rabbits to study their in vivo behavior. Scaffolds foamed with albumen displayed a monomodal pore size distribution centered around 150 μm and a porosity of 82%, whereas scaffolds foamed with H2O2 showed lower porosity (37%), with larger elongated pores, and multimodal size distribution. After 12 weeks of implantation, histology results revealed a good osteointegration for both types of scaffolds. The quantitative morphometric analysis showed the substitution of the biomaterial by new bone in the case of glasses foamed with albumen. In contrast, bone neoformation and material resorption were significantly lower in the defects filled with the scaffolds foamed with H2O2. The results obtained in this study showed that both calcium phosphate glass scaffolds were osteoconductive, biocompatible, and biodegradable materials. However, differences in porosity, pore architecture, and microstructure led to substantially different in vivo response.