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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Teixeira, S.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2021NUMERICAL SIMULATION OF SOLDER PASTE PRINTING ON THROUGH-HOLE COMPONENTS
- 2021Experimental measurements of the shear force on surface mount components simulating the wave soldering processcitations
- 2020Influence of Operating Conditions on the Thermal Behavior and Kinetics of Pine Wood Particles Using Thermogravimetric Analysiscitations
- 2018Effect of the Soldering Atmosphere on the Wettability Between Sn4.0Ag0.5Cu (in wt.%) Lead-Free Solder Paste and Various Substratescitations
- 2017Photocatalytic degradation of recalcitrant micropollutants by reusable Fe<inf>3</inf>O<inf>4</inf>/SiO<inf>2</inf>/TiO<inf>2</inf> particlescitations
- 2016Influence of Copper Layer Content in the Elastic and Damping Behavior of Glass-Fiber/Epoxy-Resin Compositescitations
- 2016TiO<inf>2</inf>/graphene oxide immobilized in P(VDF-TrFE) electrospun membranes with enhanced visible-light-induced photocatalytic performancecitations
- 2016Reusability of photocatalytic TiO <inf>2</inf> and ZnO nanoparticles immobilized in poly(vinylidene difluoride)-co-trifluoroethylenecitations
- 2016Ciprofloxacin wastewater treated by UVA photocatalysis: Contribution of irradiated TiO<inf>2</inf> and ZnO nanoparticles on the final toxicity as assessed by Vibrio fischericitations
- 2015Wetting behaviour of SAC305 solder on different substrates in high vacuum and inert atmospherecitations
- 2010In vivo evaluation of highly macroporous ceramic scaffolds for bone tissue engineeringcitations
- 2004Production of porus hydroxyapatite with potential for controlled drug delivery
- 2004Porous hydroxyapatite and glass reinforced hydroxyapatite for controlled release of sodium ampicillin
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article
In vivo evaluation of highly macroporous ceramic scaffolds for bone tissue engineering
Abstract
<p>During the last decades, different materials of both natural and synthetic origin have been developed with the aim of inducing and controlling osteogenic differentiation of mesenchymal stem cells (MSCs). In order for that to happen, it is necessary that the material to be implanted obey a series of requirements, namely: osteoconduction, biocompatibility, and biodegradability. Additionally, they must be low-priced, easy to produce, shape, and store. Hydroxyapatite (HA) is a well known ceramic with a composition similar to the mineral component of bone and is highly biocompatible and easy to obtain and/or process. On the other hand, collagen is the main structural protein present in the human body and bone. In this study, a polymer replication method was applied and a highly porous HA scaffold was produced. Collagen was later incorporated to improve the biological properties of the scaffold while resembling the bone composition. The scaffolds were characterized by means of scanning electron microscopy, Fourier transform infrared spectroscopy and energy dispersive spectroscopy. In vitro and in vivo testing was performed in all scaffolds produced. The goal of this study was to evaluate the in vivo osteogenic potential of MSCs from two different species seeded on the different HA based porous scaffolds with collagen type I. The results indicate that all scaffolds exhibit relevant bone formation, being more prominent in the case of the HA scaffolds.</p>