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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Smith, James
University of Portsmouth
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2011Multifunctional poly(alkyl methacrylate) films for dental carecitations
- 2011Electrochemical and computational studies of electrically conducting polymer coatingscitations
- 2011Mapping surface heterogeneity: the AFM-based approach
- 2011The effects of incorporated silicone oils and calcium carbonate on the resistance to settlement and the antifouling performance of a silicone elastomercitations
- 2010Towards the determination of surface energy at the nanoscale: a further assessment of the AFM-based approachcitations
- 2010A comparative study of surface energy data from atomic force microscopy and from contact angle goniometrycitations
- 2004Friction coefficient mapping using the atomic force microscopecitations
- 2002Fluoropolymer coatings with inherent resistance to biofouling
- 2002Adhesion force mapping of polymer surfaces: factors influencing force of adhesioncitations
- 2002Adsorbed poly(ethyleneoxide)–poly(propyleneoxide) copolymers on synthetic surfaces: spectroscopy and microscopy of polymer structures and effects on adhesion of skin-borne bacteriacitations
- 2001Nanoindentation and adhesion-force-mapping studies of polymer blend films
- 2000Mapping the surface heterogeneity of a polymer blend: an adhesion-force-distribution study using the Atomic Force Microscopecitations
- 2000Poly(perfluoroalkyl methacrylate) film structures: surface organization phenomena, surface energy determinations, and force of adhesion measurementscitations
Places of action
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article
Adsorbed poly(ethyleneoxide)–poly(propyleneoxide) copolymers on synthetic surfaces: spectroscopy and microscopy of polymer structures and effects on adhesion of skin-borne bacteria
Abstract
Poly(ethyleneoxide)–copoly(propyleneoxide) (PEO-PPO) polymer coatings were evaluated for their resistance to the attachment of the marker organism Serratia marcescens and the skin-borne bacteria Staphylococcus epidermidis. The copolymers were adsorbed onto poly(styrene) films—chosen as simplified physicochemical models of skin surfaces—and their surface characteristics probed by contact angle goniometry, attenuated total reflectance–Fourier transform infrared (ATR-FTIR), atomic force microscopy (AFM), and X-ray photoelectron spectroscopy (XPS). These functional surfaces were then presented to microbial cultures, bacterial attachment was assessed by fluorescence microscopy and AFM, and the structures of the polymer films examined again spectroscopically. Surface characterization data suggest that the adsorbed copolymer was partially retained at the surface and resisted bacterial attachment for 24 h. Quantitative evaluation of cell attachment was carried out by scintillation counting of 14C-labeled microorganisms in conjunction with plate counts. The results show that a densely packed layer of PEO-PPO copolymer can reduce attachment of skin commensals by an order of magnitude, even when the coating is applied by a simple adsorptive process. The work supports the hypothesis that adhesion of microorganisms to biological substrates can be reduced if a pretreatment with an appropriate copolymer can be effected in vivo. © 2002 Wiley Periodicals, Inc. J Biomed Mater Res 61: 641–652, 2002