| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Hansen, Thomas
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2024Newly developed aerodynamic levitation device for neutron scattering experiments
- 2024Impact of Mn/Ni and Li/(Mn+Ni) ratios on phase equilibrium and electrochemical performance of the high voltage spinel LiNi0.5Mn1.5O4citations
- 2023Magnetic and structural properties of the iron silicide superconductor LaFeSiH
- 2022An Easy-to-Use Custom-Built Cell for Neutron Powder Diffraction Studies of Rechargeable Batteriescitations
- 2022An Easy‐to‐Use Custom‐Built Cell for Neutron Powder Diffraction Studies of Rechargeable Batteriescitations
- 2021Investigation into the magnetic properties of CoFeNiCryCux alloyscitations
- 2021Investigation into the magnetic properties of CoFeNiCryCux alloyscitations
- 2020High-pressure, high temperature synthesis of a mesoporous α-quartz/bismuth nanowire compositecitations
- 2020Structural Characteristics of Fresh, Thermally Aged, Poisoned and Regenerated Pt-Pd Catalysts Studied by Analytical Transmission Electron Microscopy
- 2019High-pressure, high temperature insertion of bismuth in the siliceous zeolite silicalite-1citations
- 2017Absence of magnetic long range order in Y2CrSbO7: bond-disorder induced magnetic frustration in a ferromagnetic pyrochlorecitations
- 2015Expression, receptor binding, and biophysical characterization of guinea pig insulin desB30citations
- 2013Reduction of Sr2MnO4 investigated by high temperature in situ neutron powder diffraction under hydrogen flow.citations
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article
Expression, receptor binding, and biophysical characterization of guinea pig insulin desB30
Abstract
<p>Here we report, for the first time, the heterologous expression of desB30 guinea pig insulin (GI desB30) in the yeast Saccharomyces cerevisiae. The affinities of GI desB30 for the insulin receptor A and the IGF-I receptor were also quantified for the first time. Small-angle X-ray scattering and analytical ultracentrifugation studies confirmed that GI desB30 did not form dimers or hexamers, in contrast to human insulin. Sizeexclusion chromatography connected to inductively coupled plasma mass spectrometry revealed that GI desB30 has affinity towards several divalent metal ions. These studies did not indicate the formation of any larger structures of GI desB30 in the presence of various divalent metal ions, but did indicate that GI desB30 has an affinity towards Mn, Co, and Cu ions. Finally, the low affinity for the insulin receptor and the very low affinity for the IGF-I receptor by GI desB30 were quantified.</p>