| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Palmans, Ara Anja
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (36/36 displayed)
- 2024Enhanced Efficiency of Pd(0)-Based Single Chain Polymeric Nanoparticles for in Vitro Prodrug Activation by Modulating the Polymer’s Microstructurecitations
- 2023Dynamic covalent networks with tunable dynamicity by mixing acylsemicarbazides and thioacylsemicarbazidescitations
- 2022Elucidating the Stability of Single-Chain Polymeric Nanoparticles in Biological Media and Living Cellscitations
- 2022Developing Pd(ii) based amphiphilic polymeric nanoparticles for pro-drug activation in complex mediacitations
- 2022Spectrally PAINTing a Single Chain Polymeric Nanoparticle at Super-Resolutioncitations
- 2021Compartmentalized Polymers for Catalysis in Aqueous Mediacitations
- 2021Consequences of Chirality in Directing the Pathway of Cholesteric Helix Inversion of π-Conjugated Polymers by Lightcitations
- 2020Long-lived charge-transfer state from B−N frustrated Lewis pairs enchained in supramolecular copolymerscitations
- 2020Tuning polymer properties of non-covalent crosslinked PDMS by varying supramolecular interaction strengthcitations
- 2019Detailed approach to investigate thermodynamically controlled supramolecular copolymerizationscitations
- 2019Detailed approach to investigate thermodynamically controlled supramolecular copolymerizations
- 2019Stereocomplexes of discrete, isotactic lactic acid oligomers conjugated with oligodimethylsiloxanescitations
- 2019Future of supramolecular copolymers unveiled by reflecting on covalent copolymerizationcitations
- 2019Equilibrium model for supramolecular copolymerizationscitations
- 2018Supramolecular block copolymers under thermodynamic controlcitations
- 2018Supramolecular block copolymers under thermodynamic control
- 2017Self-assembly of hydrogen-bonding gradient copolymerscitations
- 2017Self-assembly of hydrogen-bonding gradient copolymers:sequence control via tandem living radical polymerization with transesterificationcitations
- 2015The coil-to-globule transition of single-chain polymeric nanoparticles with a chiral internal secondary structurecitations
- 2015Modular synthetic platform for the construction of functional single-chain polymeric nanoparticles:from aqueous catalysis to photosensitizationcitations
- 2015Modular synthetic platform for the construction of functional single-chain polymeric nanoparticlescitations
- 2014Consequences of block sequence on the orthogonal folding of triblock copolymerscitations
- 2014The effect of pendant benzene-1,3,5-tricarboxamides in the middle block of ABA triblock copolymers : synthesis and mechanical propertiescitations
- 2014Folding triblock copolymers
- 2014Folding polymers with pendant hydrogen bonding motifs in water : the effect of polymer length and concentration on the shape and size of single-chain polymeric nanoparticles
- 2014Folding polymers with pendant hydrogen bonding motifs in water : the effect of polymer length and concentration on the shape and size of single-chain polymeric nanoparticlescitations
- 2013Sticky Supramolecular Grafts Stretch Single Polymer Chainscitations
- 2013Orthogonal self-assembly in folding block copolymerscitations
- 2012Benzene-1,3,5-tricarboxamide : a versatile ordering moiety for supramolecular chemistry
- 2012Benzene-1,3,5-tricarboxamide : a versatile ordering moiety for supramolecular chemistrycitations
- 2010Hydrolases part I : enzyme mechanism, selectivity and control in the synthesis of well-defined polymerscitations
- 2007Supramolecular copolyesters with tunable properties
- 2007Supramolecular copolyesters with tunable propertiescitations
- 2007Poly(caprolactone-co-oxo-crown ether)-based poly(urethane)urea for soft tissue engineering applicationscitations
- 2006Oxo-crown-ethers as comonomers for tuning polyester properties
- 2006Oxo-crown-ethers as comonomers for tuning polyester propertiescitations
Places of action
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article
Consequences of block sequence on the orthogonal folding of triblock copolymers
Abstract
ABA- and BAB-type triblock copolymers possessing pendant, self-assembling motifs in the A and B blocks were synthesized, with 2-ureidopyrimidinone (UPy) and benzene-1,3,5-tricarboxamide (BTA) for the A and B block, respectively. They were investigated to assess if and how the polymer's microstructure influences the self-assembly behavior of the supramolecular motifs and, as a result, the single-chain folding process. BAB-type triblock copolymers were synthesized via atom transfer radical polymerization (ATRP) with molecular weights ranging from 30 to 120kgmol-1; the BTA and UPy motifs were attached using a post-functionalization approach. The ABA-type triblock copolymers were available from previous work. In highly dilute solutions, both types of triblock copolymers fold into single-chain polymeric nanoparticles (SCPNs) via thermally induced BTA self-assembly and photo-triggered UPy dimerization. Chain collapse induced by intramolecular UPy dimerization was evaluated using size-exclusion chromatography (SEC). The BTA self-assembly was monitored by circular dichroism (CD) spectroscopy. The microstructures of SCPNs were visualized by atomic force microscopy (AFM). SEC analysis indicated a more loose packing for the BAB-type folded nanoparticles than for the ABA-type ones, which implies that topological differences in the polymer architecture do affect the folding behavior, although only slightly. The facile synthetic protocol developed here provides topologically different triblock architectures and opens up the area for single-chain folding technology that is applicable in artificial enzymatic systems with compartmentalized domains. ABA- and BAB-type triblock copolymers carrying distinct self-assembling motifs in each block were designed and synthesized. These polymers fold into single-chain polymeric nanoparticles via thermal and photoirradiation treatments. An influence of block sequence on the folded structure is found, which affects the packing size of the resulting folded nanoparticles (see figure). © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.