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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Wong, F. S. L.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (4/4 displayed)
- 2013Synthesis and in-vitro cytotoxicity analysis of microwave irradiated nano-apatitescitations
- 2013Structural, mechanical, and biocompatibility analyses of a novel dental restorative nanocompositecitations
- 2013A comparison of the mechanical properties of a modified silorane based dental composite with those of commercially available composite materialcitations
- 2008Preparation and characterization of a novel bioactive restorative composite based on covalently coupled polyurethane-nanohydroxyapatite fibrescitations
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article
Structural, mechanical, and biocompatibility analyses of a novel dental restorative nanocomposite
Abstract
Structure and biocompatibility are key parameters that determine the usefulness of dental materials for clinical use. Novel polyurethane (PU) nanocomposite material was prepared by chemically binding nanohydroxyapatite (nHA) to the diisocyanate component of the PU backbone by solvent- polymerization. nHA was incorporated into PU by the stepwise addition of monomeric units of the PU. The PU/nHA composite was analyzed by 13C Nuclear magnetic resonance (structural) and X-ray diffraction (phase analysis). The tensile strength and elastic modulus was evaluated for mechanical properties. These analyses revealed linkage between the hard- and soft-segments are urethane linkage and showed high mechanical properties with increase in content of nHA. To assess biocompatibility osteoblast cells were seeded on to the material and allowed to adhere and proliferate. Osteoblast-like cell growth and proliferation was assessed by MTS assay. It was found that cells adhered and proliferated on these novel substrates. To test bacterial adhesion discs of composite with and without nHA were incubated with standardized suspensions of oral bacterium Streptococcus sanguinis strain NCTC 7863. PU composites with nHA exhibited biocompatibility with respect to mammalian cell growth and showed significantly reduced bacterial adhesion as compared to PU alone. Copyright © 2012 Wiley Periodicals, Inc.