People | Locations | Statistics |
---|---|---|
Naji, M. |
| |
Motta, Antonella |
| |
Aletan, Dirar |
| |
Mohamed, Tarek |
| |
Ertürk, Emre |
| |
Taccardi, Nicola |
| |
Kononenko, Denys |
| |
Petrov, R. H. | Madrid |
|
Alshaaer, Mazen | Brussels |
|
Bih, L. |
| |
Casati, R. |
| |
Muller, Hermance |
| |
Kočí, Jan | Prague |
|
Šuljagić, Marija |
| |
Kalteremidou, Kalliopi-Artemi | Brussels |
|
Azam, Siraj |
| |
Ospanova, Alyiya |
| |
Blanpain, Bart |
| |
Ali, M. A. |
| |
Popa, V. |
| |
Rančić, M. |
| |
Ollier, Nadège |
| |
Azevedo, Nuno Monteiro |
| |
Landes, Michael |
| |
Rignanese, Gian-Marco |
|
Royall, Paul G.
King's College London
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (8/8 displayed)
- 2023Computer numerical control (CNC) carving as an on-demand point-of-care manufacturing of solid dosage formcitations
- 2019Ocular anti-inflammatory activity of prednisolone acetate loaded chitosan-deoxycholate self-assembled nanoparticlescitations
- 2012Immersion mode material pocket dynamic mechanical analysis (IMP-DMA): A novel tool to study gelatinisation of purified starches and starch-containing plant materialscitations
- 2012Identification and molecular interpretation of the effects of drug incorporation on the self-emulsification process using spectroscopic, micropolarimetric and microscopic measurementscitations
- 2009Monitoring crystallisation of drugs from fast-dissolving oral films with isothermal calorimetrycitations
- 2005Biocompatible polymer blends: Effects of physical processing on the molecular interaction of poly(vinyl alcohol) and poly(vinyl pyrrolidone)citations
- 2001Characterization of amorphous ketoconazole using modulated temperature differential scanning calorimetrycitations
- 2001Characterization of amorphous ketoconazole using modulated temperature differential scanning calorimetrycitations
Places of action
Organizations | Location | People |
---|
article
Biocompatible polymer blends: Effects of physical processing on the molecular interaction of poly(vinyl alcohol) and poly(vinyl pyrrolidone)
Abstract
Blending is a very effective method for manufacturing new polymeric materials; however, the process used to combine two polymers can influence the physicochemical properties of the final product. As such, the aim of this study was to investigate how the rapid removal of a solvent from a composite by the spray drying of partially hydrolyzed poly(vinyl alcohol) (PVA)/poly(vinyl pyrrolidone) (PVP) altered the solid-state properties of the material compared to casting the blend within a film. Although thermal analysis showed that PVP acted as a plasticizer, reducing the melting point of PVA, spray drying the product rather than using a film-casting procedure improved its solid-state stability (increasing the glass transition) and resulted in the formation of a second crystalline phase within the material. Spectroscopic studies suggested that the manufacturing-induced variance in the solid-state properties of the PVA/PVP blends originated from structural differences in the composite caused by the processing method employed to form the blend. Although blending should still be considered a viable method of generating novel polymeric material, this study illustrated that through careful manipulation of the actual manufacturing process, the solid-state properties of the product can be altered. This could open a whole range of novel applications for traditionally used polymer composites. (c) 2005 Wiley Periodicals, Inc