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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Ganesh, Venkatraman
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article
Long-term structural and chemical stability of DNA in hydrated ionic liquids
Abstract
There is much interest in the use of DNA as an advanced material.[1] For example, DNA has been discussed as the a??ultimatea?? material for molecular computing[2] and there is much effort directed towards investigating this application. Recently, DNA has also been employed in templated chemical synthesis, nanomachines, and biosensors.[3a??5] The use of DNA as a biomaterial from a variety of readily available sources has gained importance in recent years, especially for the surface treatment of implanted materials.[6] Since it is rich in phosphate groups it has a strong affinity for bone, and DNA has been modified for use as a bone-guiding scaffold by intercalating antibiotics between the stacked base pairs.[7] The water-insoluble form of DNAalso finds a range of other applications as a biomaterial.