| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Khimyak, Yaroslav Z.
University of East Anglia
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2024Surface modification of cellulose nanomaterials with amine functionalized fluorinated ionic liquids for hydrophobicity and high thermal stabilitycitations
- 2024Self-healing composite coating fabricated with a cystamine crosslinked cellulose nanocrystal stabilized Pickering emulsioncitations
- 2022Amphiphilic Cellulose Nanocrystals for Aqueous Processing of Thermoplastics:ACS Applied Polymer Materialscitations
- 2022Amphiphilic cellulose nanocrystals for aqueous processing of thermoplasticscitations
- 2019Thermosensitive supramolecular and colloidal hydrogels via self-assembly modulated by hydrophobized cellulose nanocrystalscitations
- 2018Nanocrystallization of rare tolbutamide form V in mesoporous MCM-41 silicacitations
- 201619F NMR spectroscopy as a highly sensitive method for the direct monitoring of confined crystallization within nanoporous materialscitations
- 2016Structure and mobility of lactose in lactose/sodium montmorillonite nanocompositescitations
- 2016Structural properties, order-disorder phenomena and phase stability of orotic acid crystal formscitations
- 2010Chemical bonding assembly of multifunctional oxide nanocompositescitations
- 2009Reversible methane storage in a polymer-supported semi-clathrate hydrate at ambient temperature and pressurecitations
- 2008Bulk superconductivity at 38 K in a molecular systemcitations
- 2006Methylaminated potassium fulleride, (CH3NH2)K 3C60: Towards hyperexpanded fulleride latticescitations
Places of action
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article
19F NMR spectroscopy as a highly sensitive method for the direct monitoring of confined crystallization within nanoporous materials
Abstract
Introduction of fluorine in the structure of pharmaceuticals has been an effective strategy for tuning their pharmacodynamic properties with more than 40 new drugs accessing the market in last 15 years. In this context 19F NMR can be viewed as a useful probe for investigating the host-guest chemistry of pharmaceuticals in nanosize drug delivery systems. Although the interest in confined crystallisation, nanosize devices and porous catalysts is gradually increasing, understanding of the complex phase behavior of organic molecules confined within nano-chambers or nano-reactors is still lacking. Using 19F MAS NMR, we achieved detailed mechanistic insight into the crystallization of flufenamic acid (FFA) in a confined environment of mesoporous silicas with different pore diameters (3.2 to 29 nm), providing a direct experimental proof of the formation of a molecular liquid-like layer in addition to the crystalline confined FFA form I.