| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Werner, Peter
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (17/17 displayed)
- 2025Material Composition Gradient Controls the Autonomous Opening of Banksia Seed Pods in Fire‐Prone Habitats
- 2022A 3D Network of Nanochannels for Possible Ion and Molecule Transit in Mineralizing Bone and Cartilagecitations
- 2022Mineralization generates megapascal contractile stresses in collagen fibrilscitations
- 2020Process analytical approaches for the coil-to-globule transition of poly(N-isopropylacrylamide) in a concentrated aqueous suspension
- 2017Magnetic antiskyrmions above room temperature in tetragonal Heusler materialscitations
- 2016Superconductivity in Weyl semimetal candidate MoTe2citations
- 2016Growth and properties of self-catalyzed (In,Mn)As nanowirescitations
- 2015Stress-mediated formation of nanocrystalline calcitic microlens arrayscitations
- 2015Electron microscope analyses of the bio-silica basal spicule from the Monorhaphis chuni spongecitations
- 2015Eshelby Twist as a Possible Source of Lattice Rotation in a Perfectly Ordered Protein/Silica Structure Grown by a Simple Organismcitations
- 2014Nanocrystalline Calcitic Lens Arrays Fabricated by Self-Assembly Followed by Amorphous-to-Crystalline Phase Transformationcitations
- 2014A Perfectly Periodic Three-Dimensional Protein/Silica Mesoporous Structure Produced by an Organismcitations
- 2014Mesoporous silica: a perfectly periodic three-dimensional protein/silica mesoporous structure produced by an organism (adv. Mater. 11/2014).citations
- 2013Ferromagnetic (Ga,Mn)As nanowires grown by Mn-assisted molecular beam epitaxycitations
- 2011Effects of ad-atom diffusivity throughout Sb-mediated formation of Ge/Si nanoislands
- 2010Biodegradation of fuel oxygenates by sol-gel immobilized bacteria Aquincola tertiaricarboniscitations
- 2006Measurement of the bending strength of vapor-liquid-solid grown silicon nanowirescitations
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article
A 3D Network of Nanochannels for Possible Ion and Molecule Transit in Mineralizing Bone and Cartilage
Abstract
During crucial growth stages of vertebrate long bones, calcified cartilage beneath the growth plate is anchored to bone by a third mineralized component, the cement line. Proper skeletal development is contingent on the interplay of these three constituents, yet their mineralization processes and structural interactions are incompletely understood, in part from limited knowledge of their meso- and nanoscale features. Herein, focused ion beam-scanning electron microscopy (FIB-SEM) with serial surface imaging is applied to examine the cartilage-bone interface of mouse femoral heads at an unprecedented scale: FIB-SEM provides 3D, nanometer resolution of structural details for volumes encompassing metaphyseal calcified cartilage, bone, and the intervening cement line. A novel and complex structural network is revealed, comprising densely packed nanochannels smaller than bone canaliculi (≈10-50 nm diameter) within the calcified cartilage and bone extracellular matrices, but absent in the cement line. A structural correlation is demonstrated between the nanochannels and ellipsoidal mineral domains, which appear to coalesce during mineralization in a process analogous to powder sintering in metallurgy. A mineralization process is proposed, supported by energy-dispersive X-Ray spectroscopy of nanochannel contents, in which these unreported structures offer ion and molecule conduits to access the extracellular matrices of calcified cartilage and bone.