| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Yetisen, Ali K.
Imperial College London
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (10/10 displayed)
- 2018Highly Efficient Energy Transfer in Light Emissive Poly(9,9-dioctylfluorene) and Poly(p-phenylenevinylene) Blend Systemcitations
- 2018Functionalized flexible soft polymer optical fibers for laser photomedicinecitations
- 2018Flexible corner cube retroreflector array for temperature and strain sensingcitations
- 2018Energy Landscape of Vertically Anisotropic Polymer Blend Films toward Highly Efficient Polymer Light-Emitting Diodes (PLEDs)citations
- 2017Electrically Tunable Scattering from Devitrite-Liquid Crystal Hybrid Devicescitations
- 2017Phase-conjugated directional diffraction from a retroreflector array hologramcitations
- 2017Biodegradable elastic nanofibrous platforms with integrated flexible heaters for on-demand drug deliverycitations
- 2016Color-Selective 2.5D Holograms on Large-Area Flexible Substrates for Sensing and Multilevel Securitycitations
- 2016Nanotechnology in textilescitations
- 2014Enhanced reflection from inverse tapered nanocone arrayscitations
Places of action
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article
Functionalized flexible soft polymer optical fibers for laser photomedicine
Abstract
<p>Optical waveguides allow propagating light through biological tissue in optogenetics and photomedicine applications. However, achieving efficient light delivery to deep tissues for long-term implantation has been limited with solid-state optical fibers. Here, a method is created to rapidly fabricate flexible, functionalized soft polymer optical fibers (SPOFs) coupled with silica fibers. A step-index core/cladded poly(acrylamide-co-poly(ethylene glycol) diacrylate)/Ca alginate SPOF is fabricated through free-radical polymerization in a mold. The SPOF is integrated with a solid-state silica fiber coupler for efficient light delivery. The cladded SPOF shows ≈1.5-fold increase in light propagation compared to the noncladded fiber. The optical loss of the SPOF is measured as 0.6 dB cm<sup>-1</sup> at the bending angle of 70° and 0.28 dB cm<sup>-1</sup> through a phantom tissue. The SPOF (inner Ø = 200 μm) integrated with a 21 gauge needle (inner Ø = 514 μm) is inserted within a porcine tissue. The intensity of light decreases ≈60%, as the SPOF is implanted as deep as 2 cm. Doped with fluorescent dye and gold nanoparticles, the SPOF fiber exhibits yellow-red and red illumination. Living cells can also be incorporated within the SPOF with viability. The flexible SPOFs may have applications in photodynamic light therapy, optical biosensors, and photomedicine.</p>