| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Mackova, Anna
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (10/10 displayed)
- 2024Patterning of COC Polymers by Middle‐Energy Ion Beams for Selective Cell Adhesion in Microfluidic Devicescitations
- 2022Compositional and Structural Modifications by Ion Beam in Graphene Oxide for Radiation Detection Studiescitations
- 2022Compositional and Structural Modifications by Ion Beam in Graphene Oxide for Radiation Detection Studiescitations
- 2022The multi-energetic Au ion implantation of graphene oxide and polymerscitations
- 2022One-step 3D microstructuring of PMMA using MeV light ionscitations
- 2015Structure and Plasmonic Properties of Thin PMMA Layers with Ion-Synthesized Ag Nanoparticlescitations
- 2006Growth and modification of organosilicon films in PECVD and remote afterglow reactorscitations
- 2004Radiation-Induced Change of Polyimide Properties under High-Fluence and High Ion Current Density Implantation
- 2003Compositional alteration of polyimide under high fluence implantation by Co+ and Fe+ ionscitations
- 2002Anomalous Depth Distribution of Fe and Co Atoms in Polyimide Implanted to High Fluencecitations
Places of action
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article
Patterning of COC Polymers by Middle‐Energy Ion Beams for Selective Cell Adhesion in Microfluidic Devices
Abstract
<jats:title>Abstract</jats:title><jats:p>Microfluidic devices play a crucial role in advanced cell biology applications, including cell separations, cultivations, migration and interaction studies, diagnostic devices, and organ‐on‐chips. One of the frequent purposes of such devices is the ability to selectively address the attachment of cells at defined locations on the surface. This study explores the application of middle‐energy carbon, oxygen, and nitrogen ions to locally modify the surface of cyclic olefin copolymer (COC) thermoplastic material, allowing selective cell growth on patterned polymer surfaces. The investigation considers ion element type, ion beam energy, and ion irradiation fluence, analyzing their influence on the modification effect. Characterization of the modified surfaces involves various surface‐analytical methods such as contact angle, energy dispersive spectroscopy (SEM‐EDX), atomic force microscopy (AFM), x‐ray photoelectron spectroscopy (XPS), rutherford backscattering spectrometry (RBS), and elastic recoil detection analysis (ERDA). The study extends to practical aspects, with a representative cancer cell line, MCF‐7, grown on the patterned surface to evaluate the degree of selective attachment. Additionally, the stability of the irradiated patterns is tested under elevated temperatures beyond the glass transition temperature (<jats:italic>T</jats:italic><jats:sub>g</jats:sub>), demonstrating the compatibility of the approach with hot embossing technology. The findings underscore the potential of ion beam treatment for COC in cell‐biology‐related applications, offering insights into surface modification techniques for enhanced functionality in microfluidic devices.</jats:p>