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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Li, Yang
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (24/24 displayed)
- 2024Spin injection in graphene using ferromagnetic indium-cobalt van der Waals contacts
- 2024Sensitivity of G0 and stress-strain relation of geomaterials to grain shape and surface roughness
- 2024Triple-junction perovskite–perovskite–silicon solar cells with power conversion efficiency of 24.4%
- 2023Study of surface damage in silicon by irradiation with focused rubidium ions using a cold-atom ion sourcecitations
- 2023Near-surface characterization using Distributed Acoustic Sensing in an urban area: Granada, Spain
- 2023Bright circularly polarized photoluminescence in chiral layered hybrid lead-halide perovskitescitations
- 2023Evaporated Self‐Assembled Monolayer Hole Transport Layers: Lossless Interfaces in <i>p‐i‐n</i> Perovskite Solar Cellscitations
- 2023Silver contamination and its toxicity and risk management in terrestrial and aquatic ecosystemscitations
- 2022Fiber orientation dependence of tribological behavior of short carbon fiber reinforced ceramic matrix compositescitations
- 2022Elastic and inelastic mean free paths for scattering of fast electrons in thin-film oxidescitations
- 2021Premelting and formation of ice due to Casimir-Lifshitz interactions: Impact of improved parameterization for materials ; ENEngelskEnglishPremelting and formation of ice due to Casimir-Lifshitz interactions: Impact of improved parameterization for materialscitations
- 2021Exciton versus free carrier emission: Implications for photoluminescence efficiency and amplified spontaneous emission thresholds in quasi-2D and 3D perovskitescitations
- 2020Rapid and cytocompatible cell-laden silk hydrogel formation via riboflavin-mediated crosslinking
- 2020Rapid and cytocompatible cell-laden silk hydrogel formation via riboflavin-mediated crosslinkingcitations
- 2019Electrochemical metallization ReRAMs (ECM) - Experiments and modellingcitations
- 2019Volumetric Bioprinting of Complex Living-Tissue Constructs within Secondscitations
- 2018Magnetically activated microcapsules as controlled release carriers for a liquid PDMS cross-linkercitations
- 2016Transient phases during fast crystallization of organic thin films from solutioncitations
- 2014Design of anodic aluminum oxide rear surface plasmonic heterostructures for light trapping in thin silicon solar cellscitations
- 2012Characterization of epitaxial GaAs MOS capacitors using atomic layer-deposited TiO2/Al2O3gate stack: study of Ge auto-doping and p-type Zn doping
- 2009Lanthanide N,N '-piperazine-bis(methylenephosphonates) (Ln = La, Ce, Nd) that display flexible frameworks, reversible hydration and cation exchangecitations
- 2007Confinement of Thermoresponsive Hydrogels in Nanostructured Porous Silicon Dioxide Templatescitations
- 2007Confinement of Thermoresponsive Hydrogels in Nanostructured Porous Silicon Dioxide Templatescitations
- 2005Synthesis and characterization of CdS quantum dots in polystyrene microbeadscitations
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article
Volumetric Bioprinting of Complex Living-Tissue Constructs within Seconds
Abstract
Biofabrication technologies, including stereolithography and extrusion-based printing, are revolutionizing the creation of complex engineered tissues. The current paradigm in bioprinting relies on the additive layer-by-layer deposition and assembly of repetitive building blocks, typically cell-laden hydrogel fibers or voxels, single cells, or cellular aggregates. The scalability of these additive manufacturing technologies is limited by their printing velocity, as lengthy biofabrication processes impair cell functionality. Overcoming such limitations, the volumetric bioprinting of clinically relevant sized, anatomically shaped constructs, in a time frame ranging from seconds to tens of seconds is described. An optical-tomography-inspired printing approach, based on visible light projection, is developed to generate cell-laden tissue constructs with high viability (>85%) from gelatin-based photoresponsive hydrogels. Free-form architectures, difficult to reproduce with conventional printing, are obtained, including anatomically correct trabecular bone models with embedded angiogenic sprouts and meniscal grafts. The latter undergoes maturation in vitro as the bioprinted chondroprogenitor cells synthesize neo-fibrocartilage matrix. Moreover, free-floating structures are generated, as demonstrated by printing functional hydrogel-based ball-and-cage fluidic valves. Volumetric bioprinting permits the creation of geometrically complex, centimeter-scale constructs at an unprecedented printing velocity, opening new avenues for upscaling the production of hydrogel-based constructs and for their application in tissue engineering, regenerative medicine, and soft robotics.