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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Pina, S.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (33/33 displayed)
- 2024Characterization of Iron Oxide Nanotubes Obtained by Anodic Oxidation for Biomedical Applications—In Vitro Studiescitations
- 2022Osteogenic lithium-doped brushite cements for bone regenerationcitations
- 2021Porous aligned ZnSr-doped β-TCP/silk fibroin scaffolds using ice-templating method for bone tissue engineering applicationscitations
- 2021Scaffold Fabrication Technologies and Structure/Function Properties in Bone Tissue Engineeringcitations
- 2021Ion-doped Brushite Cements for Bone Regenerationcitations
- 2020Hierarchical HRP-crosslinked silk fibroin/ZnSr-doped TCP nancocomposites towards osteochondral tissue regeneration: Biomechanical performance and in vivo assessment
- 2017Biofunctional Ionic-Doped Calcium Phosphates: Silk Fibroin Composites for Bone Tissue Engineering Scaffoldingcitations
- 2016Influence of Mg-doping, calcium pyrophosphate impurities and cooling rate on the allotropic α↔β-tricalcium phosphate phase transformationscitations
- 2016Biomimetic strategies to engineer mineralized human tissuescitations
- 2015Cartilage and Bone Regeneration-How Close Are We to Bedside?citations
- 2015Natural-based nanocomposites for bone tissue engineering and regenerative medicine: a reviewcitations
- 2015Calcium phosphates-based biomaterials with Sr- and Zn-dopants for osteochondral tissue engineeringcitations
- 2014Effects of Mn-doping on the structure and biological properties of β-tricalcium phosphatecitations
- 2014Calcium phosphate bone cements
- 2012Calcium phosphate bone cements
- 2012The bioactivity mechanism of magnetron sputtered bioglass thin filmscitations
- 2012Bioresorbable plates and screws for clinical applications: A reviewcitations
- 2011Highly adherent bioactive glass thin films synthetized by magnetron sputtering at low temperaturecitations
- 2011Melt-derived condensed polymorphic calcium phosphate as bone substitute material: An in vitro studycitations
- 2011Synthesis, mechanical and biological characterization of ionic doped carbonated hydroxyapatite/β-tricalcium phosphate mixturescitations
- 2010Bioactive glass thin films deposited by magnetron sputtering technique: The role of working pressurecitations
- 2010Injectability of brushite-forming Mg-substituted and Sr-substituted α-TCP bone cementscitations
- 2010Newly developed Sr-substituted α-TCP bone cementscitations
- 2010Synthesis and structural characterization of strontium- and magnesium-co-substituted β-tricalcium phosphatecitations
- 2010Biomineralization capability of adherent bio-glass films prepared by magnetron sputteringcitations
- 2010In vitro performance assessment of new brushite-forming Zn- and ZnSr-substituted β-TCP bone cementscitations
- 2010Erratum: Biomineralization capability of adherent bio-glass films prepared by magnetron sputtering Journal of Materials Science: Materials in Medicine DOI: 10.1007/s10856-009-3940-9)citations
- 2010Biological responses of brushite-forming Zn-and ZnSr-substituted β-Tricalcium phosphate bone cements
- 2009Influence of setting liquid composition and liquid-to-powder ratio on properties of a Mg-substituted calcium phosphate cementcitations
- 2008An in vitro biological and anti-bacterial study on a sol-gel derived silver-incorporated bioglass systemcitations
- 2006Formation of strontium-stabilized β-tricalcium phosphate from calcium-deficient apatitecitations
- 2005Interfacial interactions between liquid new biocompatible model glasses and solid metallic and ceramic substrates used in biomedicine
- 2005Effect of isomorphic substitutions on crystallization of mica and amphibole phases in glasses of the system SiO2-Al2O 3-B2O3-CaO-MgO-Li2O-(K,Na) 2O-F
Places of action
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article
Natural-based nanocomposites for bone tissue engineering and regenerative medicine: a review
Abstract
Tissue engineering and regenerative medicine has been providing exciting technologies for the development of functional substitutes aimed to repair and regenerate damaged tissues and organs. Inspired by the hierarchical nature of bone, nanostructured biomaterials are gaining a singular attention for tissue engineering, owing their ability to promote cell adhesion and proliferation, and hence new bone growth, compared with conventional microsized materials. Of particular interest are nanocomposites involving biopolymeric matrices and bioactive nanosized fi llers. Biodegradability, high mechanical strength, and osteointegration and formation of ligamentous tissue are properties required for such materials. Biopolymers are advantageous due to their similarities with extracellular matrices, specifi c degradation rates, and good biological performance. By its turn, calcium phosphates possess favorable osteoconductivity, resorbability, and biocompatibility. Herein, an overview on the available natural polymer/calcium phosphate nanocomposite materials, their design, and properties is presented. Scaffolds, hydrogels, and fi bers as biomimetic strategies for tissue engineering, and processing methodologies are described. The specifi c biological properties of the nanocomposites, as well as their interaction with cells, including the use of bioactive molecules, are highlighted. Nanocomposites in vivo studies using animal models are also reviewed and discussed. ; The research leading to this work has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement no REGPOT-CT2012-316331-POLARIS, and from QREN (ON.2 - NORTE-01-0124-FEDER-000016) cofinanced by North Portugal Regional Operational Program (ON.2 - O Novo Norte), under the National Strategic Reference Framework (NSRF), through the European Regional Development Fund (ERDF).