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Peter, Karlheinz
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article
Nanoporous Metal-Phenolic Particles as Ultrasound Imaging Probes for Hydrogen Peroxide.
Abstract
Nanoporous metal-phenolic particles are fabricated through the nanostructural replication of dense Fe<sup>III</sup> -TA complexes in nanoporous CaCO<sub>3</sub> template particles. The particles have potential for the diagnostic detection of endogenous levels of H<sub>2</sub> O<sub>2</sub> ex vivo and in vivo by ultrasound imaging, which is based on the catalytic activity of the coordinated Fe<sup>3+</sup> in the particles to break down H<sub>2</sub> O<sub>2</sub> to O<sub>2</sub> microbubbles.