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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Schweizer, Peter
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (11/11 displayed)
- 2024Temporally-resolved decomposition of Ti 0.12 Al 0.21 B 0.67 thin films at 1000 °Ccitations
- 2024Temporally-resolved decomposition of Ti0.12Al0.21B0.67 thin films at 1000°Ccitations
- 2024Unraveling the highly plastic behavior of ALD‐aluminum oxide encapsulations by small‐scale tensile testingcitations
- 2024Unraveling interdiffusion phenomena and the role of nanoscale diffusion barriers in the copper-gold systemcitations
- 2024Unraveling the Highly Plastic Behavior of ALD‐Aluminum Oxide Encapsulations by Small‐Scale Tensile Testingcitations
- 2024Well-defined synthesis of crystalline MnO, Mn 2 O 3 , and Mn 3 O 4 phases by anodic electrodeposition and calcinationcitations
- 2023Microwave plasma-assisted reactive HiPIMS of InN films: plasma environment and material characterisationcitations
- 2023Microwave plasma-assisted reactive HiPIMS of InN films: Plasma environment and material characterisationcitations
- 2023Surface chemistry dictates the osteogenic and antimicrobial properties of palladium-, platinum-, and titanium-based bulk metallic glassescitations
- 2022Composition dependent electrical transport in Si 1−x Ge x nanosheets with monolithic single-elementary Al contactscitations
- 2022Monolithic and single-crystalline aluminum-silicon heterostructurescitations
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article
Surface chemistry dictates the osteogenic and antimicrobial properties of palladium-, platinum-, and titanium-based bulk metallic glasses
Abstract
Titanium alloys are commonly used as biomaterials in musculoskeletal applications, but their long-term efficacy can be limited by wear and corrosion, stress shielding, and bacterial colonization. As a promising alternative, bulk metallic glasses (BMGs) offer superior strength and corrosion resistance, but the influence of their chemical composition on their bioactivity remains largely unexplored. This study, therefore, aims to examine how the surface chemistry of palladium (Pd)-, platinum (Pt)-, and titanium (Ti)-based BMGs can steer their response to biological systems. The chemical composition of BMGs governs their thermophysical and mechanical properties, with Pd-based BMGs showing exceptional glass-forming ability suitable for larger implants, and all BMGs exhibiting a significantly lower Young's modulus than Ti-6Al-4 V (Ti64), suggesting a potential to reduce stress shielding. Although BMGs feature copper depletion at the near surface, their surface chemistry remains more stable than that of Ti64 and supports blood biocompatibility. Fibrin network formation is heavily dependent on BMGs' chemical composition and Ti-based BMGs support thicker fibrin network formation than Ti64. Furthermore, BMGs outperform Ti64 in promoting mineralization of human bone progenitor cells and demonstrate antimicrobial properties against Staphylococcus aureus in a surface chemistry-dependent manner, thereby indicating their great potential as biomaterials for musculoskeletal applications.