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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Schweins, Ralf
Institut Laue-Langevin
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (39/39 displayed)
- 2023The H-D-isotope effect of heavy water affecting ligand-mediated nanoparticle formation in SANS and NMR experimentscitations
- 2023The Effects of Amino Acid Functionalisation on the Optoelectronic Properties and Self-Assembly of Perylene Bisimidescitations
- 2023Aggregation Behavior of Nonsymmetrically End-Capped Thermoresponsive Block Copolymers in Aqueous Solutions: Between Polymer Coils and Micellar States
- 2023Arabinoxylan in Water through SANS: Single-Chain Conformation, Chain Overlap, and Clusteringcitations
- 2023Nanostructure in Amphiphile-Based Deep Eutectic Solventscitations
- 2023Potential of Small‐Angle Neutron Scattering for Evaluating Protein Locus within a Polymersomecitations
- 2022Resolving the different bulk moduli within individual soft nanogels using small-angle neutron scatteringcitations
- 2022How Temperature Rise Can Induce Phase Separation in Aqueous Biphasic Solutionscitations
- 2022Aggregation Behavior of Nonsymmetrically End-Capped Thermoresponsive Block Copolymers in Aqueous Solutions: Between Polymer Coils and Micellar Statescitations
- 2022Aggregation Behavior of Nonsymmetrically End-Capped Thermoresponsive Block Copolymers in Aqueous Solutions: Between Polymer Coils and Micellar Statescitations
- 2022Aggregation behavior of nonsymmetrically end-capped thermoresponsive block copolymers in aqueous solutionscitations
- 2021Direct Structural Evidence for Interfacial Gradients in Asymmetric Polymer Nanocomposite Blendscitations
- 2021Stress driven creep deformation and cavitation damage in pure coppercitations
- 2021Water-accessibility of interfibrillar spaces in spruce wood cell wallscitations
- 2020Efficiency Boosting of Surfactants with Poly(ethylene oxide)-Poly(alkyl glycidyl ether)s: A New Class of Amphiphilic Polymerscitations
- 2020Observing microfibril bundles in wood by small-angle neutron scattering
- 2020Using Small-Angle Scattering and Contrast Matching to Understand Molecular Packing in Low Molecular Weight Gelscitations
- 2020Using small-angle scattering and contrast matching to understand molecular packing in low molecular weight gelscitations
- 2020An in-depth analysis approach enabling precision single chain nanoparticle designcitations
- 2020Fluorination of Diamond Nanoparticles in Slow Neutron Reflectors Does Not Destroy Their Crystalline Cores and Clustering While Decreasing Neutron Lossescitations
- 2020Bundling of cellulose microfibrils in native and polyethylene glycol-containing wood cell walls revealed by small-angle neutron scatteringcitations
- 2020Moisture-related changes in the nanostructure of woods studied with X-ray and neutron scatteringcitations
- 2019Multicore Liquid Perfluorocarbon-Loaded Multimodal Nanoparticles for Stable Ultrasound and 19 F MRI Applied to In Vivo Cell Trackingcitations
- 2019Small-angle scattering model for efficient characterization of wood nanostructure and moisture behaviourcitations
- 2018Deswelling behaviour of ionic microgel particles from low to ultra-high densitiescitations
- 2018Preparation of Polymer Brush Grafted Anionic or Cationic Silica Nanoparticles: Systematic Variation of the Polymer Shellcitations
- 2016Interplay between Polymer Chain Conformation and Nanoparticles Assembly in Model Industrial Silica/Rubber Nanocompositescitations
- 2015Analysis of the structure of nanocomposites of triglyceride platelets and DNAcitations
- 2015Origin of Small-Angle Scattering from Contrast-Matched Nanoparticles: A Study of Chain and Filler Structure in Polymer Nanocompositescitations
- 2015Chain signal in nanolatex based nanocomposites
- 2014X-Ray Tomography and Small-Angle Neutron Scattering Characterization of Nano-Composites:Static and In Situ Experimentscitations
- 2013Magnetization reversal in Nd-Fe-B based nanocomposites as seen by magnetic small-angle neutron scatteringcitations
- 2013Effect of Grafting on Rheology and Structure of a Simplified Industrial Nanocomposite Silica/SBRcitations
- 2013Effect of grafting on rheology and structure of a simplified industrial nanocomposite silica/SBR.citations
- 2012Polymer-Grafted Magnetic Nanoparticles in Nanocomposites: Curvature Effects, Conformation of Grafted Chain, and Bimodal Nanotriggering of Filler Organization by Combination of Chain Grafting and Magnetic Fieldcitations
- 2011Responsive hybrid block co-polymer conjugates of proteins–controlled architecture to modulate substrate specificity and solution behaviourcitations
- 2011Reinforcement and Polymer Mobility in Silica–Latex Nanocomposites with Controlled Aggregationcitations
- 2010Direct small angle neutron scattering observation of stretched chain conformation in nanocomposites: more insight of polymer contributions in mechanical reinforcementcitations
- 2010Amphiphilic dual brush block copolymers as "giant surfactants" and their aqueous self-assemblycitations
Places of action
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article
Multicore Liquid Perfluorocarbon-Loaded Multimodal Nanoparticles for Stable Ultrasound and 19 F MRI Applied to In Vivo Cell Tracking
Abstract
<p>Ultrasound is the most commonly used clinical imaging modality. However, in applications requiring cell-labeling, the large size and short active lifetime of ultrasound contrast agents limit their longitudinal use. Here, 100 nm radius, clinically applicable, polymeric nanoparticles containing a liquid perfluorocarbon, which enhance ultrasound contrast during repeated ultrasound imaging over the course of at least 48 h, are described. The perfluorocarbon enables monitoring the nanoparticles with quantitative<sup>19</sup>F magnetic resonance imaging, making these particles effective multimodal imaging agents. Unlike typical core–shell perfluorocarbon-based ultrasound contrast agents, these nanoparticles have an atypical fractal internal structure. The nonvaporizing highly hydrophobic perfluorocarbon forms multiple cores within the polymeric matrix and is, surprisingly, hydrated with water, as determined from small-angle neutron scattering and nuclear magnetic resonance spectroscopy. Finally, the nanoparticles are used to image therapeutic dendritic cells with ultrasound in vivo, as well as with<sup>19</sup>F MRI and fluorescence imaging, demonstrating their potential for long-term in vivo multimodal imaging.</p>