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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Lahann, Joerg
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (20/20 displayed)
- 2024Photo‐Arbuzov Reactions as a Broadly Applicable Surface Modification Strategycitations
- 2022Surfaces Decorated with Enantiomorphically Pure Polymer Nanohelices via Hierarchical Chirality Transfer across Multiple Length Scalescitations
- 2020Systemic brain tumor delivery of synthetic protein nanoparticles for glioblastoma therapycitations
- 2020Molecular Changes in Vapor‐Based Polymer Thin Films Assessed by Characterization of Swelling Properties of Amine‐Functionalized Poly‐p-xylylene
- 2018Surface-initiated RAFT polymerization from vapor-based polymer coatingscitations
- 2018Water‐Stable Nanoporous Polymer Films with Excellent Proton Conductivitycitations
- 2017Polylutidinescitations
- 2017Polylutidines: Multifunctional Surfaces through Vapor-Based Polymerization of Substituted Pyridinophanescitations
- 2017pH-responsive aminomethyl functionalized poly(p-xylylene) coatings by chemical vapor deposition polymerizationcitations
- 2017Electrospun Polymer Fiber Lasers for Applications in Vapor Sensingcitations
- 2017Electrospun Polymer Fiber Lasers for Applications in Vapor Sensingcitations
- 2016Optical sensors from electrohydrodynamic jetted polymer fiber resonatorscitations
- 2016Optical sensors from electrohydrodynamic jetted polymer fiber resonatorscitations
- 2015Hierarchically Functionalized Magnetic Core/Multishell Particles and Their Postsynthetic Conversion to Polymer Capsulescitations
- 2015Free-Standing Nanomembranes Based on Selective CVD Deposition of Functional Poly- p -xylylenescitations
- 2014Fabrication of Highly Uniform Gel Coatings by the Conversion of Surface-Anchored Metal-Organic Frameworkscitations
- 2014Biofunctional Micropatterning of Thermoformed 3D Substratescitations
- 2014Interaction of Human Plasma Proteins with Thin Gelatin-Based Hydrogel Films: A QCM-D and ToF-SIMS Studycitations
- 2013Co-immobilization of Biomolecules on Ultrathin Reactive Chemical Vapor Deposition Coatings Using Multiple Click Chemistry Strategiescitations
- 2011Engineering, characterization and directional self-assembly of anisotropically modified nanocolloidscitations
Places of action
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article
Biofunctional Micropatterning of Thermoformed 3D Substrates
Abstract
Mimicking the in vivo microenvironment of cells is a challenging task in engineering in vitro cell models. Surface functionalization is one of the key components providing biochemical cues to regulate the interaction between cells and their substrate. In this study, two different approaches yield biofunctional surface patterns on thermoformed polymer films. The first strategy based on maskless projection lithography enables the creation of grayscale patterns of biological ligands with a resolution of 7.5 µm in different shapes on a protein layer adsorbed on a polymer film. In the second strategy, polymer films are micropatterned with different functional groups via chemical vapor deposition polymerization. After thermoforming, both types of pattern can be decorated with proteins either by affinity binding or covalent coupling. The 3d microstructures retain the biofunctional patterns as demonstrated by selective cell adhesion and growth of l929 mouse fibroblasts. This combination of functional micropatterning and thermoforming offers new perspectives for the design of 3d cell culture platforms.