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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Schmidt, Stephan
Graz University of Technology
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (6/6 displayed)
- 2023The Internal Structure of the Velvet Worm Projectile Slime: A Small-Angle Scattering Study.citations
- 2023Developing a level-1B qualifiable CNN for in-situ ultrasonic damage classification of aerospace composite structures: An in-depth evaluation on the end-to-end process of developing a data-driven tool
- 2018Combustion Analysis with Residual Gas as a Design Parameter for Two-Stroke Engines
- 2012Control of cell adhesion by mechanical reinforcement of soft polyelectrolyte films with nanoparticlescitations
- 2011Release properties of pressurized microgel templated capsulescitations
- 2010Adhesion and mechanical properties of PNIPAM microgel films and their potential use as switchable cell culture substratescitations
Places of action
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article
Release properties of pressurized microgel templated capsules
Abstract
Direction-specific release induced through osmotic pressure inside giant microcapsules is realized and monitored at high and low concentrations of encapsulated polymer. A clear correlation between the release kinetics upon opening the shell and encapsulated polymer concentration is observed. This has been independently confirmed by shell opening via nanoindentation and laser radiation. To quantify these observations, the internal pressure of the capsules is determined by analysis of mechanical tests performed via colloidal probe AFM. As expected, larger amounts of encapsulated material lead to increased internal pressures and enhanced release kinetics. The results show how drug release can be accelerated by encapsulation of osmotic pressure generating species. Such pressurized capsules systems show large ejection velocities and are envisioned as an inexpensive biolistic transfection device for in vitro applications.