| People | Locations | Statistics |
|---|---|---|
| Grohsjean, Alexander |
| |
| Falmagne, G. |
| |
| Erice, C. |
| |
| Hernandez, A. M. Vargas |
| |
| Leiton, A. G. Stahl |
| |
| Lipka, K. |
| |
| Pantaleo, F. |
| |
| Torterotot, L. |
| |
| Savina, M. |
| |
| Cerri, O. |
| |
| Jung, A. W. |
| |
| Chiarito, B. |
| |
| Sahin, M. O. |
| |
| Strong, G. |
| |
| Saradhy, R. |
| |
| Joshi, B. M. |
| |
| Kaynak, B. |
| |
| Barrera, C. Baldenegro |
| |
| Longo, Egidio |
| |
| Kolberg, Ted |
| |
| Ferguson, Thomas |
| |
| Leverington, Blake |
| |
| Haase, Fabian |
| |
| Heath, Helen F. |
| |
| Kokkas, Panagiotis |
|
Piozzi, Antonella
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (23/23 displayed)
- 2023Rice husk ash as a green feedstock for the extraction of nano-silica and its application in the synthesis of an efficient solid biocatalyst
- 2020Enhanced performance of Candida rugosa lipase immobilized onto alkyl chain modified-magnetic nanocompositescitations
- 2017Taurine grafting and collagen adsorption on PLLA films improve human primary chondrocyte adhesion and growthcitations
- 2016Flexible aliphatic poly(isocyanurate-oxazolidone) resins based on poly(ethylene glycol) diglycidyl ether and 4,4′-methylene dicyclohexyl diisocyanatecitations
- 2015Self-Assembly of catecholic moiety-containing cationic random acrylic copolymerscitations
- 2015Antimicrobial and antioxidant amphiphilic random copolymers to address medical device-centered infectionscitations
- 2014Biomimetic Polyurethanescitations
- 2014Partially sulfonated ethylene-vinyl alcohol copolymer as new substrate for 3,4-ethylenedioxythiophene vapor phase polymerizationcitations
- 2013Editorial of the special issue antimicrobial polymerscitations
- 2012A new approach for the preparation of hydrophilic poly(L-lactide) porous scaffold for tissue engineering by using lamellar single crystalscitations
- 2012Lipase Immobilization on Differently Functionalized Vinyl-Based Amphiphilic Polymers: Influence of Phase Segregation on the Enzyme Hydrolytic Activitycitations
- 2012Synthesis of biomimetic segmented polyurethanes as antifouling biomaterialscitations
- 2010Novel intrinsically antimicrobial polymers to control biofilm formation on medical devices
- 2010Synthesis and properties of block poly(ether-ester)s based on poly(ethylene oxide) and various hydrophobic segmentscitations
- 2010Polyurethane anionomers containing metal ions with antimicrobial properties: Thermal, mechanical and biological characterizationcitations
- 2009Antibiofilm properties of functionalized polyurethanes adsorbed with metal ions (Ag+, Cu2+, Zn2+, Al3+ and Fe3+)
- 2007Synthesis, characterization, and in vitro activity of antibiotic releasing polyurethanes to prevent bacterial resistancecitations
- 2007Staphylococcus epidermidis biofilm growth on polyurethanes is inhibited by the synergistic action of Dispersin B and cefamandole nafate.
- 2005Inhibition of Candida growth and biofilm formation on polyurethanes by fluconazole adsorption.citations
- 2004Inhibition of bacterial biofilm formation on polymer surfaces by a natural antimicrobial agent
- 2004Inhibition of biofilm formation in Gram-positive bacteria by a natural antimicrobial agent
- 2001CATALITIC ACTIVITY OF IMMOBILIZED FUMARASEcitations
- 2000Sulfation and preliminary biological evaluation of ethylene-vinyl alcohol copolymerscitations
Places of action
| Organizations | Location | People |
|---|
conferencepaper
Antibiofilm properties of functionalized polyurethanes adsorbed with metal ions (Ag+, Cu2+, Zn2+, Al3+ and Fe3+)
Abstract
This research is focused on the development of intrinsically antimicrobial polyurethanes in which the carboxyl groups present in the polymer backbone were neutralized with Ag+, Cu2+, Zn2+, Al3+ and Fe3+. The antimicrobial activity of these metal ion-containing polyurethanes was studied alone or in combination with ciprofloxacin (CPF). Aims of the study were to evaluate the most efficacious ions in counteracting microbial growth on polymeric surfaces and to assess the possible synergistic role of ciprofloxacin. An acidic polyetherurethane (PEUA), containing one carboxyl group per repetitive unit, was turned into PEUA-Ag, PEUA-Cu, PEUA-Zn, PEUA-Al and PEUA-Fe by treatment with equimolar amounts of the salts AgNO3, Cu(CH3COO)2, ZnNO3, AlCl3 and Fe(NO3)3, respectively. The obtained polymers were characterized by mechanical and swelling tests. The antibacterial efficacy of the metal ion-containing polymers, alone or treated with ciprofloxacin, was evaluated against Staphylococcus epidermidis ATCC 35984 by: i) the Kirby Bauer test; ii) the count of colony forming units (CFUs) per polymer surface unit; iii) the observation of microbial biofilm formation on the polymer surface by scanning electron microscopy. Due to the interaction between the ionic groups leading to physical cross-linking, metal ion-containing polymers exhibited better mechanical properties in terms of hardness and strength at break than the pristine PEUA. With the exception of PEUA-Al, all the other polymers showed significant antimicrobial properties. The best antibacterial effect was obtained by the PEUA-Ag for its ability to inhibit the S. epidermidis biofilm formation up to 16 days. The ciprofloxacin adsorption to the polymers prolonged their antimicrobial activity, demonstrating a synergistic antibiofilm effect of PEUA-Ag-CPF up to 25 days. Our experiments suggest that: i) carboxylated polyurethanes can coordinate antimicrobial metal ions offering a simple methodology to obtain intrinsically antibiofilm polyurethanes; ii) the methodology employed ...