| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Daiuto, F.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2023Characterization of Nanosized Carbide Precipitates in Multiple Microalloyed Press Hardening Steelscitations
- 2023β-Tricalcium Phosphate-Loaded Chitosan-Based Thermosensitive Hydrogel for Periodontal Regeneration.citations
- 2020Welding between aluminum alloy and steel sheets by using transition jointscitations
- 2019A Full-Field Calibration Approach on Material Parameter Identification
- 2014Dissimilar arc welding of advanced high-strength car-body steel sheetscitations
- 2014Residual formability of preformed and subsequently welded advanced high strength steels (Reform) ; Restumformbarkeit vorgeformter und anschließend geschweißter hochfester Mehrphasenstähle (Reform)
- 2013Resistance Spot Welding of Advanced High Strength TWIP Steelscitations
- 2012Hydrogen Embrittlement Of Automotive Advanced High-Strength Steelscitations
- 2010Association Between Interleukin-6-174 Polymorphism and Aggregatibacter actinomycetemcomitans in Chronic Periodontitis
- 2010Plastic localization phenomena in a Mn-alloyed austenitic steelcitations
- 2009Plastic localization phenomena in a Mn-alloyed austenitic steel
- 2008Interleukin-6 polymorphisms are associated with pathogenic bacteria in subjects with periodontitiscitations
- 2008Portevin - Le Chatelier effect in a Mn-alloyed thermomechanically processed austenitic steel
Places of action
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article
β-Tricalcium Phosphate-Loaded Chitosan-Based Thermosensitive Hydrogel for Periodontal Regeneration.
Abstract
The current treatment for periodontitis is aimed at resolving gingival inflammation, whilst complete periodontal tissue regeneration is not predictable, and it represents a therapeutic challenge. Injectable biomaterials hold tremendous potential in dental tissue regeneration. This study aimed to investigate the ability of an injectable thermosensitive β-tricalcium phosphate (β-TCP) and chitosan-based hydrogel to carry cells and promote periodontal tissue regeneration. In this study, different concentrations of β-TCP-loaded chitosan hydrogels were prepared (0%, 2%, 4%, or 6% β-TCP, 10% β-glycerol phosphate, and 1.5% chitosan). The characteristics of the hydrogels were tested using rheology, a scanning electron microscope (SEM), X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), degradation, and biological analyses. The new biomaterial showed a sol-gel transformation ability at body temperature and exhibited excellent chemical and physical characteristics, whilst the existence of β-TCP enhanced the structure and the properties of the hydrogels. The SEM confirmed the three-dimensional networks of the hydrogels, and the typical rheological properties of strong gel were observed. The EDX and XRD validated the successful incorporation of β-TCP, and similar patterns between different groups were found in terms of the FTIR spectra. The stable structure of the hydrogels under 100 °C was confirmed via DSC. Biological tests such as Alamar Blue assay and Live/Dead staining confirmed the remarkable biocompatibility of the hydrogels with pre-osteoblast MC3T3-E1 and human gingival fibroblast (HGF) cells for 14 days, and the results were validated with confocal imaging. This preliminary study shows great promise for the application of the β-TCP-loaded thermosensitive chitosan hydrogels as a scaffold in periodontal bone and soft tissue repair.