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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Asif, Muhammad
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2024Genetic polymorphisms in FABP2, CYP2E1, and TP53 genes are potentially associated with colorectal cancer susceptibility
- 2024MOF derived metal oxide nanohybrids with <i>in situ</i> grown rGO: a smart material for simultaneous electrochemical sensing of HQ and RScitations
- 2024Investigating the Compressive Response of Hand-Laminated GFRP Pipes in the Hoop Direction through Experiment and FEM Modelingcitations
- 2023Design of high gain base station antenna array for mm-wave cellular communication systemscitations
- 2023Association of GSTTI, M1 and Polymorphism in GSTPI with Chronic Periodontal Disease in a Pakistani Populationcitations
- 2022The Effect of Infrared Laser Irradiation on the Surface Morphology and Electrical Properties of Zinc Metalcitations
- 2021Experimental validation of bulk-graphene as a thermoelectric generatorcitations
- 2020Investigation on the effects of the processing parameters and the number of passes on the flexural properties of polymer nanocomposite fabricated through FSP method
- 2019Investigation of the strain-rate-dependent mechanical behavior of a photopolymer matrix composite with fumed nano-silica fillercitations
- 2019In-situ dynamic response measurement for damage quantification of 3D printed ABS cantilever beam under thermomechanical loadcitations
- 2012Characterization of Common Fusion Oncogenes As Prognostic Molecular Identities in Adult Acute Lymphoblastic Leukemia Identifies the Need for Genetic Testing At Presentation, Molecular Prognostication and Differential Treatment
- 2011Intracellular K(+) Determination With a Potentiometric Microelectrode Based on ZnO Nanowirescitations
- 2010Intracellular ZnO Nanorods Conjugated with Protoporphyrin for Local Mediated Photochemistry and Efficient Treatment of Single Cancer Cellcitations
- 2010Functionalized ZnO nanorod-based selective magnesium ion sensor for intracellular measurementscitations
Places of action
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article
Association of GSTTI, M1 and Polymorphism in GSTPI with Chronic Periodontal Disease in a Pakistani Population
Abstract
<jats:p>Objective: Chronic periodontal disease (CP) is a multifactorial infectious and inflammatory disease that occurs due to the challenge between the immune response of the host and specific periodontal bacteria, and that can lead to tooth loss due to damage inflicted to the supporting tissue. The current study investigates the genotypes of the GSTM1 and GSTT1 genes, along with the allelic frequency of the single nucleotide polymorphism [SNP; rs1695] in the GSTP1 gene and correlates them individually or in various combinations with the incidence of CP. Methods: A total of 203 clinically confirmed CP patients and 201 control subjects were enrolled from Multan and Dera Ghazi Khan Districts in Pakistan from April to July 2022. Multiplex Polymerase Chain Reaction (PCR) and tetra-primer amplification refractory mutation system–polymerase chain reaction (T-ARMS–PCR) approaches were applied to determine the genotypes of the studied GSTs. The association of rs1695 in GSTP1 with CP was studied both individually and in various combinations with GSTM1 and T1. Results: The absence of GSTM1, the presence of GSTT1 and the presence of the mutant allele (G) at rs1695 in GSTP1 were found to be significantly associated with CP. Patients aged between 10 and 30 years were more affected by CP. Conclusion: Our results indicate that the genotypes of the analyzed GSTs affect the levels of protection from oxidative stress and may therefore influence the disease progression in CP.</jats:p>