| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Gomes, Ps
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2021Assessment of the Bone Healing Process Mediated by Periosteum-Derived Mesenchymal Stem Cells' Secretome and a Xenogenic Bioceramic-An In Vivo Study in the Rabbit Critical Size Calvarial Defect Model.citations
- 2018Processing, characterization, and in vivo evaluation of poly (L-lactic acid)-fish gelatin electrospun membranes for biomedical applicationscitations
- 2018Development of bioactive tellurite-lanthanide ions-reinforced hydroxyapatite composites for biomedical and luminescence applicationscitations
- 2017Incorporation of glass-reinforced hydroxyapatite microparticles into poly(lactic acid) electrospun fibre mats for biomedical applicationscitations
- 2016Effect of Sterilization Methods on Electrospun Poly(lactic acid) (PLA) Fiber Alignment for Biomedical Applicationscitations
- 2015Smart electroconductive bioactive ceramics to promote in situ electrostimulation of bonecitations
- 2015Novel cerium doped glass-reinforced hydroxyapatite with antibacterial and osteoconductive properties for bone tissue regenerationcitations
- 2014Processing strategies for smart electroconductive carbon nanotube-based bioceramic bone graftscitations
- 2013Development and characterization of lanthanides doped hydroxyapatite composites for bone tissue applicationcitations
- 2012Development and Characterization of Ag2O-Doped ZnLB Glasses and Biological Assessment of Ag2O-ZnLB-Hydroxyapatite Compositescitations
- 2010Evaluation of human osteoblastic cell response to plasma-sprayed silicon-substituted hydroxyapatite coatings over titanium substratescitations
- 2010New titanium and titanium/hydroxyapatite coatings on ultra-high-molecular-weight polyethylene-in vitro osteoblastic performancecitations
- 2009Assessment of the osteoblastic cell response to a zinc glass reinforced hydroxyapatite composite (Zn-GRHA)citations
- 2008Biocompatibility evaluation of DLC-coated Si3N4 substrates for biomedical applicationscitations
Places of action
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article
Development and Characterization of Ag2O-Doped ZnLB Glasses and Biological Assessment of Ag2O-ZnLB-Hydroxyapatite Composites
Abstract
This work aims to report the preparation, physico-chemical characterization, antibacterial activity, and biocompatibility testing of novel Ag-containing ZnOLi(2)OB(2)O(3)HA composites, which are intended to be applied in bone tissue regenerative applications. Silver oxide (0.5, 1, 2, and 4 mol%) doped ZnOLi2OB2O3 (Ag(2)OZLB) glasses were prepared by conventional quenching techniques. The newly developed glasses were characterized by X-ray diffraction, Raman and Fourier transforms infrared spectroscopy, and Scanning electron microscopy. Furthermore, glass-ceramic composites (Ag(2)OZnLBHA composites) were obtained by the mixture of 2.5 wt% of each silver glass with 97.5 wt% of hydroxyapatite, and thoroughly characterized. The initial bacteria adhesion was evaluated using Escherichia coli, whereas the biocompatibility profile of these materials was assessed following the establishment of MG63 osteoblast-like cell cultures, for 7 days. All the assayed compositions revealed a significant antibacterial activity against E. coli, at early culture time points. Moreover, osteoblastic cells revealed an adequate adhesion to all the assayed Ag(2)OZnLBHA compositions and following, an active proliferation was established over seeded materials, throughout the culture period. No signs of cytotoxicity were attained by the assessment of cell morphology, viability, and proliferation. Furthermore, the composites containing a higher amount of silver (2 Ag(2)OZnLBHA and 4 Ag(2)OZnLBHA) allowed an increased cell proliferation, in comparison with control.