| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
| |
| Motta, Antonella |
| |
| Aletan, Dirar |
| |
| Mohamed, Tarek |
| |
| Ertürk, Emre |
| |
| Taccardi, Nicola |
| |
| Kononenko, Denys |
| |
| Petrov, R. H. | Madrid |
|
| Alshaaer, Mazen | Brussels |
|
| Bih, L. |
| |
| Casati, R. |
| |
| Muller, Hermance |
| |
| Kočí, Jan | Prague |
|
| Šuljagić, Marija |
| |
| Kalteremidou, Kalliopi-Artemi | Brussels |
|
| Azam, Siraj |
| |
| Ospanova, Alyiya |
| |
| Blanpain, Bart |
| |
| Ali, M. A. |
| |
| Popa, V. |
| |
| Rančić, M. |
| |
| Ollier, Nadège |
| |
| Azevedo, Nuno Monteiro |
| |
| Landes, Michael |
| |
| Rignanese, Gian-Marco |
|
Gernaey, Krist V.
Technical University of Denmark
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (12/12 displayed)
- 2024Production of phosphate biofertilizers as a booster for the techno-economic and environmental performance of a first-generation sugarcane ethanol and sugar biorefinerycitations
- 2023The effects of low oxidation-reduction potential on the performance of full-scale hybrid membrane-aerated biofilm reactorscitations
- 2022Economic and environmental analysis of bio-succinic acid production: from established processes to a new continuous fermentation approach with in-situ electrolytic extractioncitations
- 2019A Simulation-Based Superstructure Optimization Approach for Process Synthesis and Design Under Uncertainty
- 2018Mechanistic modeling of cyclic voltammetry: A helpful tool for understanding biosensor principles and supporting design optimizationcitations
- 2018Rapid and Efficient Development of Downstream Bio-Pharmaceutical Processing Alternatives
- 2014The Electrical Breakdown of Thin Dielectric Elastomerscitations
- 2013Applying mechanistic models in bioprocess development.citations
- 2013Applying mechanistic models in bioprocess development.citations
- 2012Evaluation of the energy efficiency of enzyme fermentation by mechanistic modelingcitations
- 2010Embedded resistance wire as a heating element for temperature control in microbioreactorscitations
- 2008Multivariate models for prediction of rheological characteristics of filamentous fermentation broth from the size distributioncitations
Places of action
| Organizations | Location | People |
|---|
article
Embedded resistance wire as a heating element for temperature control in microbioreactors
Abstract
This paper presents the technical realization of a low-cost heating element consisting of a resistance wire in a microbioreactor, as well as the implementation and performance assessment of an on/off controller for temperature control of the microbioreactor content based on this heating element. The microbioreactor (working volume of 100 mu L) is designed to work bubble-free, and is fabricated out of the polymers poly(methylmethacrylate) (PMMA) and poly(dimethylsiloxane) (PDMS). The temperature is measured with a Pt 100 sensor, and the resistance wires are embedded in the polymer such that they either surround the reactor chamber or are placed underneath it. The latter can achieve an even temperature distribution across the reactor chamber and direct heating of the reactor content. We show that an integrated resistance wire coupled to a simple on/off controller results in accurate temperature control of the reactor (+/- 0.1 degrees C of the set point value) and provides a good disturbance rejection capability (corrective action for a sudden temperature drop of 2.5 degrees C at an operating temperature of 50 degrees C takes less than 30 s). Finally, we also demonstrate the workability of the established temperature control in a batch Saccharomyces cerevisiae cultivation in a microbioreactor.