| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Thormann, Esben
Technical University of Denmark
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (17/17 displayed)
- 2024Reducing Ice Adhesion to Polyelectrolyte Surfaces by Counterion-Mediated Nonfrozen Hydration Watercitations
- 2023A Biomimetic Water-Resistant Adhesive Based on ϵ-Polylysine/Tannic Acid Complexationcitations
- 2023Fibrin Adsorption on Cardiovascular Biomaterials and Medical Devicescitations
- 2021A pH-responsive polyelectrolyte multilayer film with tunable interfacial propertiescitations
- 2021A pH-responsive polyelectrolyte multilayer film with tunable interfacial propertiescitations
- 2021pH-responsive chitosan nanofilms crosslinked with genipincitations
- 2021pH-Responsive Chitosan Nanofilms Crosslinked with Genipincitations
- 2020Water Diffusion in Polymer Composites Probed by Impedance Spectroscopy and Time-Resolved Chemical Imagingcitations
- 2020Surface forces and friction tuned by thermo-responsive polymer filmscitations
- 2020Surface forces and friction tuned by thermo-responsive polymer filmscitations
- 2018An engineered cell-imprinted substrate directs osteogenic differentiation in stem cellscitations
- 2018An engineered cell-imprinted substrate directs osteogenic differentiation in stem cellscitations
- 2014Direct measurement of colloidal interactions between polyaniline surfaces in a uv-curable coating formulation:the effect of surface hydrophilicity/ hydrophobicity and resin compositioncitations
- 2014Direct measurement of colloidal interactions between polyaniline surfaces in a uv-curable coating formulationcitations
- 2013Tribological Properties Mapping: Local Variation in Friction Coefficient and Adhesioncitations
- 2012Adsorption and protein-induced metal release from chromium metal and stainless steelcitations
- 2011Toward Homogeneous Nanostructured Polyaniline/Resin Blendscitations
Places of action
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article
An engineered cell-imprinted substrate directs osteogenic differentiation in stem cells
Abstract
A cell-imprinted poly(dimethylsiloxane)/hydroxyapatite nanocomposite substrate was fabricated to engage topographical, mechanical, and chemical signals to stimulate and boost stem cell osteogenic differentiation. The physicochemical properties of the fabricated substrates, with nanoscale resolution of osteoblast morphology, were probed using a wide range of techniques including scanning electron microscopy, atomic force microscopy, dynamic mechanical thermal analysis, and water contact angle measurements. The osteogenic differentiation capacity of the cultured stem cells on these substrates was probed by alizarin red staining, ALP activity, osteocalcin measurements, and gene expression analysis. The outcomes revealed that the concurrent roles of the surface patterns and viscoelastic properties of the substrate provide the capability of directing stem cell differentiation toward osteogenic phenotypes. Besides the physical and mechanical effects, we found that the chemical signaling of osteoinductive hydroxyapatite nanoparticles, embedded in the nanocomposite substrates, could further improve and optimize stem cell osteogenic differentiation.