| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Achadu, Ojodomo J.
Teesside University
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2024Nanomaterials and their use in bioelectronic medicine
- 2024Insight into the electrochemical performance of heavy metal-free quantum dots in different buffered ferricyanide/ferrocyanide redox systemscitations
- 2024Molecularly Imprinted Viral Protein Integrated Zn−Cu−In−Se−P Quantum Dots Superlattice for Quantitative Ratiometric Electrochemical Detection of SARS-CoV‑2 Spike Protein in Salivacitations
- 2024An organic-inorganic polyacrylamide-based surface imprinted quantum dots for the impedimetric and voltammetric detection of diazepam in saliva with smartphone readoutcitations
- 2024Molecularly Imprinted Viral Protein Integrated Zn-Cu-In-Se-P Quantum Dots Superlattice for Quantitative Ratiometric Electrochemical Detection of SARS-COV-2 Spike Protein in Salivacitations
- 2024Molecularly imprinted viral protein integrated Zn-Cu-In-Se-P quantum dots superlattice for quantitative ratiometric electrochemical detection of SARS-CoV-2 spike protein in salivacitations
- 2023Blue-emitting SiO 2 -coated Si-doped ZnSeS quantum dots conjugated aptamer-molecular beacon as an electrochemical and metal-enhanced fluorescence biosensor for SARS-CoV-2 spike proteincitations
- 2023Blue-emitting SiO2-coated Si-doped ZnSeS quantum dots conjugated aptamer-molecular beacon as an electrochemical and metal-enhanced fluorescence biosensor for SARS-CoV-2 spike proteincitations
- 2022Amoxicillin Encapsulation on Alginate/Magnetite Composite and Its Antimicrobial Properties Against Gram-Negative and Positive Microbescitations
- 2020Fluorescent and electrochemical dual-mode detection of Chikungunya virus E1 protein using fluorophore-embedded and redox probe-encapsulated liposomescitations
- 2018In-situ synthesis of gold nanoparticles on graphene quantum dots-phthalocyanine nanoplatformscitations
- 2017Nonlinear Interactions of Zinc Phthalocyanine-Graphene Quantum Dots Nanocompositescitations
- 2016Application of graphene quantum dots decorated with TEMPO-derivatized zinc phthalocyanine as novel nanoprobescitations
Places of action
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article
Molecularly Imprinted Viral Protein Integrated Zn-Cu-In-Se-P Quantum Dots Superlattice for Quantitative Ratiometric Electrochemical Detection of SARS-COV-2 Spike Protein in Saliva
Abstract
Solution-processable colloidal quantum dots (QDs) are promising materials for the development of rapid and low-cost, next-generation quantum-sensing diagnostic systems. In this study, we report on the synthesis of multinary Zn-Cu-In-Se-P (ZCISeP) QDs and the application of the QDs-modified electrode (QDs/SPCE) as a solid superlattice transducer interface for the ratiometric electrochemical detection of the SARS-CoV-2-S1 protein in saliva. The ZCISeP QDs were synthesized through the formation of In(Zn)PSe QDs from InP QDs, followed by the incorporation of Cu cations into the crystal lattice via cation exchange processes. A viral-protein-imprinted polymer film was deposited onto the QDs/SPCE for the specific binding of SARS-CoV-2. Molecular imprinting of the virus protein was achieved using a surface imprinting electropolymerization strategy to create the MIP@QDs/SPCE nanosensor. Characterization through spectroscopic, microscopic, and electrochemical techniques confirmed the structural properties and electronic-band state of the ZCISeP QDs. Cyclic voltammetry studies of the QDs/SPCE superlattice confirmed efficient electron transport properties and revealed an intraband gap energy state with redox peaks attributed to the Cu 1+/2+ defects. Binding of SARS-CoV-2-S1 to the MIP@QDs/SPCE cavities induced a gating effect that modulated the Fe(CN) 6 3-/4- and Cu 1+/2+ redox processes at the nanosensor interface, producing dual off/on ratiometric electrical current signals. Under optimal assay conditions, the nanosensor exhibited a wide linear detection range (0.001-100 pg/mL) and a low detection limit (0.34 pg/mL, 4.6 fM) for quantitative detection of SARS-CoV-2-S1 in saliva. The MIP@QDs/SPCE nanosensor demonstrated excellent selectivity against nonspecific protein targets, and the integration with a smartphone-based potentiostat confirmed the potential for point-of-care applications.