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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Damia, Chantal
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (12/12 displayed)
- 2022Laser powder bed fusion of ultra-high-molecular-weight polyethylene/hydroxyapatite composites for bone tissue engineeringcitations
- 2021Chemical Functionalization of Calcium Phosphate Bioceramic Surfacescitations
- 2019Pre-osteoblast cell colonization of porous silicon substituted hydroxyapatite bioceramics: Influence of microporosity and macropore designcitations
- 2019Functionalization of Hydroxyapatite Ceramics: Raman Mapping Investigation of Silanizationcitations
- 2019Functionalization of Hydroxyapatite Ceramics: Raman Mapping Investigation of Silanizationcitations
- 2017Functionalisation of silicon substituted hydroxyapatite bioceramics by BMP-2 for bone tissue engineering
- 2016Hydroxyapatite microporous bioceramics as vancomycin reservoir: Antibacterial efficiency and biocompatibility investigationcitations
- 2016Quantitative analysis of vascular colonisation and angio-conduction in porous silicon-substituted hydroxyapatite with various pore shapes in a chick chorioallantoic membrane (CAM) modelcitations
- 2015Elaboration of osteoinductive phosphocalcic bioceramics for bone tissue engineering
- 2014In vitro and in vivo evaluation of silicated hydroxyapatite and impact of insulin adsorptioncitations
- 2011Processing, physico-chemical characterisation and in vitro evaluation of silicon containing β-tricalcium phosphate ceramicscitations
- 2010Surface transformation of silicon-doped hydroxyapatite immersed in culture medium under dynamic and static conditionscitations
Places of action
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article
Processing, physico-chemical characterisation and in vitro evaluation of silicon containing β-tricalcium phosphate ceramics
Abstract
International audience ; For bone grafting applications, the elaboration of silicon containing beta-tricalcium phosphate (β-TCP) was studied. The synthesis was performed using a wet precipitation method according to the hypothetical theoretical formula Ca3−x(PO4)2−2x(SiO4)x. Two silicon loaded materials (0.46 wt.% and 0.95 wt.%) were investigated and compared to a pure β-TCP. The maturation time of the synthesis required in order to obtain β-TCP decreased with the amount of silicon. Only restrictive synthesis conditions allow preparing silicon containing β-TCP with controlled composition. To obtain dense ceramics, the sintering behaviour of the powders was evaluated. The addition of silicon slowed the densification process and decreased the grain size of the dense ceramics. Rietveld refinement may indicate a partial incorporation of silicon in the β-TCP lattice. X-ray photoelectron spectroscopy and transmission electron microscopy analyses revealed that the remaining silicon formed amorphous clusters of silicon rich phase. The in vitro biological behaviour was investigated with MC3T3-E1 osteoblast-like cells. After the addition of silicon, the ceramics remained cytocompatible, highlighting the high potential of silicon containing β-TCP as optimised bone graft material.