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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Jastrzębska, Agnieszka
Warsaw University of Technology
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (42/42 displayed)
- 2023Excellent antimicrobial and photocatalytic performance of C/GO/TiO2/Ag and C/TiO2/Ag hybrid nanocomposite beds against waterborne microorganismscitations
- 2023Waste iron as a robust and ecological catalyst for decomposition industrial dyes under UV irradiationcitations
- 2023Application of Micron-Sized Zero-Valent Iron (ZVI) for Decomposition of Industrial Amaranth Dyes
- 2023Ambient Processed rGO/Ti<sub>3</sub>CNT<sub><i>x</i></sub> MXene Thin Film with High Oxidation Stability, Photosensitivity, and Self-Cleaning Potentialcitations
- 2023Novel photo-Fenton nanocomposite catalyst based on waste iron chips-Ti3C2T MXene for efficient water decontaminationcitations
- 2022Tunable Antibacterial Activity of a Polypropylene Fabric Coated with Bristling Ti<sub>3</sub>C<sub>2</sub>T<sub><i>x</i></sub> MXene Flakes Coupling the Nanoblade Effect with ROS Generationcitations
- 2022Modelling and Characterisation of Residual Stress of SiC-Ti3C2Tx MXene Composites Sintered via Spark Plasma Sintering Methodcitations
- 2021Microstructure and Mechanical Properties of Alumina Composites with Addition of Structurally Modified 2D Ti3C2 (MXene) Phasecitations
- 2021Multifunctional carbon-supported bioactive hybrid nanocomposite (C/GO/NCP) bed for superior water decontamination from waterborne microorganismscitations
- 2021Antimicrobial performance of Ti3C3 MXene-based point-of-use water filters
- 2021Synthesis, characterization and biophysical evaluation of the 2D Ti2CTx MXene using 3D spheroid-type culturescitations
- 2021Influence of Ti3C2Tx MXene and Surface-Modified Ti3C2Tx MXene Addition on Microstructure and Mechanical Properties of Silicon Carbide Composites Sintered via Spark Plasma Sintering Methodcitations
- 2021Biological and Corrosion Evaluation of In Situ Alloyed NiTi Fabricated through Laser Powder Bed Fusion (LPBF)citations
- 2021A Review on Development of Ceramic-Graphene Based Nanohybrid Composite Systems in Biological Applicationscitations
- 2021Filtration Materials Modified with 2D Nanocomposites—A New Perspective for Point-of-Use Water Treatmentcitations
- 2020Influence of MXene (Ti3C2) Phase Addition on the Microstructure and Mechanical Properties of Silicon Nitride Ceramicscitations
- 2020Controlling the Porosity and Biocidal Properties of the Chitosan-Hyaluronate Matrix Hydrogel Nanocomposites by the Addition of 2D Ti3C2Tx MXenecitations
- 2019Ti2C MXene Modified with Ceramic Oxide and Noble Metal Nanoparticles: Synthesis, Morphostructural Properties, and High Photocatalytic Activitycitations
- 20192D Ti2C (MXene) as a novel highly efficient and selective agent for photothermal therapycitations
- 2019Influence of modification of Ti3C2MXene with ceramic oxide and noble metal nanoparticles on its antimicrobial properties and ecotoxicity towards selected algae and higher plantscitations
- 2019The toxicity in vitro of titanium dioxide nanoparticles modified with noble metals on mammalian cellscitations
- 2019Praseodymium doped nanocrystals and nanocomposites for application in white light sourcescitations
- 2019The studies of cytotoxicity and antibacterial activity of composites with ZnO-doped bioglasscitations
- 2019Silicon carbide matrix composites reinforced with two-dimensional titanium carbide – manufacturing and propertiescitations
- 2017Mechanical properties of graphene oxide reinforced alumina matrix composites citations
- 2017Synthesis and Bioactivity of RGO/TiO2-Noble Metal Nanocomposite Flakescitations
- 2017Controlled synthesis of graphene oxide/alumina nanocomposites using a new dry sol–gel method of synthesiscitations
- 2017Surface modification of graphene oxide nanoplatelets and its influence on mechanical properties of alumina matrix compositescitations
- 2017Biosorption properties of RGO/Al2O3 nanocomposite flakes modified with Ag, Au, and Pd for water purificationcitations
- 2017Controlling the microstructure of lyophilized porous biocomposites by the addition of ZnO-doped bioglasscitations
- 2017Comparative Assessment of Biocidal Activity of Different RGO/Ceramic Oxide-Ag Nanocompositescitations
- 2016Synthesis of the RGO/Al2O3 core-shell nanocomposite flakes and characterization of their unique electrostatic properties using zeta potential measurementscitations
- 2016Synthesis and Bioactivity of Reduced Graphene Oxide/Alumina-Noble Metal Nanocomposite Flakes
- 2016Synthesis of RGO/TiO2 nanocomposite flakes and characterization of their unique electrostatic properties using zeta potential measurementscitations
- 2015The ecotoxicity of graphene family materials: current status, knowledge gaps and future needscitations
- 2015New reduced graphene oxide/alumina (RGO/Al2O3) nanocomposite: innovative method of synthesis and characterizationcitations
- 2015Influence of the Staphylococcus Aureus Bacteria Cells on the Zeta Potential of Graphene Oxide Modified with Alumina Nanoparticles in Electrolyte and Drinking Water Environmentcitations
- 2015The Impact of Zeta Potential and Physicochemical Properties of TiO2-Based Nanocomposites on Their Biological Activitycitations
- 2014Nano-titanium oxide doped with gold, silver and palladium – synthesis and structural characterizationcitations
- 2013Influence of Al2O3/Pr Nanoparticles on Soil, Air and Water Microorganismscitations
- 2011Al2O3‐Ag nanopowders: new method of synthesis, characterisation and biocidal activitycitations
- 2010Producing and properties of the polylactide-alumina nanocomposite fibres
Places of action
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article
Synthesis, characterization and biophysical evaluation of the 2D Ti2CTx MXene using 3D spheroid-type cultures
Abstract
Ceramics International 47 (2021) 22567–22577Available online 3 May 20210272-8842/© 2021 Elsevier Ltd and Techna Group S.r.l. All rights reserved.Synthesis, characterization and biophysical evaluation of the 2D Ti2CTx MXene using 3D spheroid-type cultures Gim Pao Lima, Chin Fhong Soona,*, Agnieszka Maria Jastrzębskad, Nyuk Ling Mac, Anita Rozmysłowska Wojciechowskad, Aleksandra Szuplewskad, Wan Ibtisam Wan Omara, Marlia Morsina, Nafarizal Nayana, Kian Sek Teeb aBiosensor and Bioengineering Lab, Microelectronics and Nanotechnology-Shamsuddin Research Center, Institute for Integrated Engineering, Universiti Tun Hussein Onn Malaysia, 86400, Parit Raja, Batu Pahat, Johor, Malaysia bFaculty of Electrical and Electronic Engineering, Universiti Tun Hussein Onn Malaysia, 86400, Parit Raja, Batu Pahat, Johor, Malaysia cFaculty of Science and Marine Environment, Universiti Malaysia Terengganu, 21030, Kuala Nerus, Terengganu, Malaysia dFaculty of Materials Science and Engineering, Warsaw University of Technology, 02-507, Warsaw, Wołoska 141, PolandARTICLE INFOKeywords: MAX phase MXenes Ti2CTx Cytotoxicity in vitro 3D cell model Spheroids ABSTRACTMXenes are novel 2-D materials which have been extensively investigated for use in advanced biocomposites, water purification, biosensors, bioimaging and antibacterial systems. However, the knowledge associated with the mechanism ofcytotoxic response isstill limited to lack ofverification against 3D spheroid-type cultures. Herein, we present a report on the in vitro cytotoxicity of Ti2CTx MXene against cervical cancer cell lines (HeLa) in a form of 3D spheroid with comparison to 2D cell culture system. Ti2CTx MXenes can be characterized by their multi-layered structure that is produced by the efficient elimination of Al and appearance of the surface func-tional groups. The biological results with 2D and 3D HeLa indicated that the Ti2CTx MXene was moderately cytotoxic to cells and the cytotoxicity was dose dependent. Our results showed that the toxicity of MXenes is potentially due to direct contact of the Ti2CTx MXene with the cell membrane wall. The Raman spectra suggested that the Ti2CTx MXenes interfered with the cytoplasmic proteins’ conformation and the surrounding microen-vironment. This inherently modified the biochemistry of the cell membrane and caused cell apoptosis. This paper contributes to the pool of knowledge regarding the biocompatibility and biophysical properties of Ti2CTx MXene.