| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Monteiro, Fj
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (15/15 displayed)
- 2023Full physicochemical and biocompatibility characterization of a supercritical CO2 sterilized nano-hydroxyapatite/chitosan biodegradable scaffold for periodontal bone regenerationcitations
- 202145S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Methodcitations
- 2020Femtosecond laser microstructuring of alumina toughened zirconia for surface functionalization of dental implantscitations
- 2019Influence of PLLA/PCL/HA Scaffold Fiber Orientation on Mechanical Properties and Osteoblast Behaviorcitations
- 2019Inhibitory Effect of 5-Aminoimidazole-4-Carbohydrazonamides Derivatives Against Candida spp. Biofilm on Nanohydroxyapatite Substratecitations
- 2018Highly porous 45S5 bioglass-derived glass-ceramic scaffolds by gelcasting of foamscitations
- 2018Micropatterned Silica Films with Nanohydroxyapatite for Y-TZP Implantscitations
- 2016Biodegradation, biocompatibility, and osteoconduction evaluation of collagen-nanohydroxyapatite cryogels for bone tissue regenerationcitations
- 2014Modulation of human dermal microvascular endothelial cell and human gingival fibroblast behavior by micropatterned silica coating surfaces for zirconia dental implant applicationscitations
- 2014Influence of nanohydroxyapatite surface properties on Staphylococcus epidermidis biofilm formationcitations
- 2012Adhesion of Staphylococcus aureus, Staphylococcus epidermidis, and Pseudomonas aeruginosa onto nanohydroxyapatite as a bone regeneration materialcitations
- 2008PLD bioactive ceramic films: the influence of CaO-P(2)O(5) glass additions to hydroxyapatite on the proliferation and morphology of osteblastic like-cellscitations
- 2004Production of porus hydroxyapatite with potential for controlled drug delivery
- 2004Porous hydroxyapatite and glass reinforced hydroxyapatite for controlled release of sodium ampicillin
- 2000Microstructural dependence of Young's and shear moduli of P2O5 glass reinforced hydroxyapatite for biomedical applicationscitations
Places of action
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article
Femtosecond laser microstructuring of alumina toughened zirconia for surface functionalization of dental implants
Abstract
The continuous need for high-performance implants that can withstand mechanical loads while promoting implant integration into bone has focused recent research on the surface modification of hard ceramics. Their properties of biocompatibility, high mechanical and fatigue resistance and aesthetic color have contributed to its succefull applications in dentistry. Alumina toughened Zirconia (ATZ) has been gaining attention as a material for dental implants applications due to its advanced mechanical properties and minimal degradation at body temperature. Still, in order to improve tissue response to this bioinert material, additional modifications are desirable. Improving the surface functionality of this ceramic could lead to enhanced implant-tissue interaction and subsequently, a successful implant integration. In this work, microtopographies were developed on the surface of Alumina toughened Zirconia using an ultrafast laser methodology, aiming at improving the cellular response to this ceramic. Microscale grooves and grid-like geometries were produced on ATZ ceramics by femtosecond laser ablation, with a pulse width of 150 fs, wavelength of 800 nm and repetition rate of 1 kHz. The variation of surface topography, roughness, chemistry and wettability with different laser processing parameters was examined. Cell-surface interactions were evaluated for 7 days on both microstructured surfaces and a non-treated control with pre-osteoblasts, MC3T3-E1 cells. Both surface topographies showed to improve cell response, with increased metabolic activity when compared to the untreated control and modulating cell morphology up to 7 days. The obtained results suggest that femtosecond laser texturing may be a suitable non-contact methodology for creating tunable micro-scale surface topography on ATZ ceramics to enhance the biological response.