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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Grover, Liam, M.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (10/10 displayed)
- 2023Tailoring absorptivity of highly reflective Ag powders by pulsed-direct current magnetron sputtering for additive manufacturing processescitations
- 2022Surface Free Energy Dominates the Biological Interactions of Postprocessed Additively Manufactured Ti-6Al-4Vcitations
- 2021Formulation of a Composite Nasal Spray Enabling Enhanced Surface Coverage and Prophylaxis of SARS-COV-2citations
- 2021Surface finish of additively manufactured metalscitations
- 2020Selective laser melting of ti-6al-4vcitations
- 2018Formulation and viscoelasticity of mineralised hydrogels for use in bone-cartilage interfacial reconstructioncitations
- 2018Tailoring selective laser melting process for titanium drug-delivering implants with releasing micro-channelscitations
- 2016Hollow spheres as nanocomposite fillers for aerospace and automotive composite materials applicationscitations
- 2016Development of 5-(4,6-dichlorotriazinyl) aminofluorescein (DTAF) staining for the characterisation of low acyl gellan microstructurescitations
- 2011Enhanced stability and local structure in biologically relevant amorphous materials containing pyrophosphatecitations
Places of action
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article
Tailoring selective laser melting process for titanium drug-delivering implants with releasing micro-channels
Abstract
The use of drug-delivering implants can minimise implant failure due to infection through a controlled medication release into the surrounding tissues. In this study, selective laser melting (SLM) was employed to manufacture Ti-6Al-4 V samples, with internal reservoirs and releasing Micro-channels (MCs) to simulate what could be a drug-delivering orthopaedic or dental implant. Investigations were performed to optimise the design and SLM process parameters required to create the releasing MCs with minimum dimensional deviation to allow a controlled dosing of the drugs, while considering the process impact on the surface roughness and porosity of the builds. The build orientation, internal contour spacing, and laser process parameters were varied to assess their effect on the resolution of the MCs with diameters of ∼200–500 μm. It was found that, vertically oriented channels were found to have the least dimensional deviation from the target dimensions compared with horizontally-oriented or inclined channels. The dimensional deviation of the MCs was found in range of 220–427 μm, while the horizontal surface roughness (Ra) was in range of 1.46–11.46 μm and the vertical surface roughness (R<sub>a</sub>) was in range of 8.5–13.23 μm when applying energy density varying from of 27–200 J/mm3. It was found that, there was a clear correlation between the energy density with both dimensional deviation and horizontal surface roughness, while no correlation was found for the vertical’ surface roughness. The study identified the optimum conditions to manufacture drug-delivering metallic implants, creating hollow samples with releasing MCs equivalent diameter of ∼271 μm, horizontal surface roughness (R<sub>a</sub>) of 4.4 μm, vertical surface roughness of (R<sub>a</sub>) 9.2 μm, and build porosity of 1.4% using an internal contour of 150 μm and energy density of 35.7 J/mm<sup>3</sup>.