Materials Map

Discover the materials research landscape. Find experts, partners, networks.

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The Materials Map is an open tool for improving networking and interdisciplinary exchange within materials research. It enables cross-database search for cooperation and network partners and discovering of the research landscape.

The dashboard provides detailed information about the selected scientist, e.g. publications. The dashboard can be filtered and shows the relationship to co-authors in different diagrams. In addition, a link is provided to find contact information.

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The Materials Map is still under development. In its current state, it is only based on one single data source and, thus, incomplete and contains duplicates. We are working on incorporating new open data sources like ORCID to improve the quality and the timeliness of our data. We will update Materials Map as soon as possible and kindly ask for your patience.

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Naji, M.
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Fernandes, Mh

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in Cooperation with on an Cooperation-Score of 37%

Topics

Publications (25/25 displayed)

  • 2023Titanium dioxide nanoparticles affect osteoblast-derived exosome cargos and impair osteogenic differentiation of human mesenchymal stem cells15citations
  • 2023Full physicochemical and biocompatibility characterization of a supercritical CO2 sterilized nano-hydroxyapatite/chitosan biodegradable scaffold for periodontal bone regeneration25citations
  • 2022Fabrication of a biodegradable and cytocompatible magnesium/ nanohydroxyapatite/fluorapatite composite by upward friction stir processing for biomedical applications32citations
  • 202145S5 Bioglass-Derived Glass-Ceramic Scaffolds Containing Niobium Obtained by Gelcasting Method6citations
  • 2020Femtosecond laser microstructuring of alumina toughened zirconia for surface functionalization of dental implants72citations
  • 2019Influence of PLLA/PCL/HA Scaffold Fiber Orientation on Mechanical Properties and Osteoblast Behavior25citations
  • 2019Inhibitory Effect of 5-Aminoimidazole-4-Carbohydrazonamides Derivatives Against Candida spp. Biofilm on Nanohydroxyapatite Substrate7citations
  • 2018Processing, characterization, and in vivo evaluation of poly (L-lactic acid)-fish gelatin electrospun membranes for biomedical applications4citations
  • 2018Femtosecond laser impact on calcium phosphate bioceramics assessed by micro-Raman spectroscopy and osteoblastic behaviour9citations
  • 2018Development of bioactive tellurite-lanthanide ions-reinforced hydroxyapatite composites for biomedical and luminescence applications2citations
  • 2018Highly porous 45S5 bioglass-derived glass-ceramic scaffolds by gelcasting of foams15citations
  • 2018Micropatterned Silica Films with Nanohydroxyapatite for Y-TZP Implants4citations
  • 2017Incorporation of glass-reinforced hydroxyapatite microparticles into poly(lactic acid) electrospun fibre mats for biomedical applications22citations
  • 2016Biodegradation, biocompatibility, and osteoconduction evaluation of collagen-nanohydroxyapatite cryogels for bone tissue regeneration59citations
  • 2016Effect of Sterilization Methods on Electrospun Poly(lactic acid) (PLA) Fiber Alignment for Biomedical Applications195citations
  • 2015Smart electroconductive bioactive ceramics to promote in situ electrostimulation of bone24citations
  • 2015Novel cerium doped glass-reinforced hydroxyapatite with antibacterial and osteoconductive properties for bone tissue regeneration54citations
  • 2014Modulation of human dermal microvascular endothelial cell and human gingival fibroblast behavior by micropatterned silica coating surfaces for zirconia dental implant applications34citations
  • 2014Processing strategies for smart electroconductive carbon nanotube-based bioceramic bone grafts6citations
  • 2013Development and characterization of lanthanides doped hydroxyapatite composites for bone tissue application21citations
  • 2012Development and Characterization of Ag2O-Doped ZnLB Glasses and Biological Assessment of Ag2O-ZnLB-Hydroxyapatite Composites11citations
  • 2010Evaluation of human osteoblastic cell response to plasma-sprayed silicon-substituted hydroxyapatite coatings over titanium substrates54citations
  • 2010New titanium and titanium/hydroxyapatite coatings on ultra-high-molecular-weight polyethylene-in vitro osteoblastic performance8citations
  • 2009Assessment of the osteoblastic cell response to a zinc glass reinforced hydroxyapatite composite (Zn-GRHA)1citations
  • 2005In vitro studies of calcium phosphate glass ceramics with different solubility with the use of human bone marrow cells15citations

Places of action

Chart of shared publication
Piperni, Sg
1 / 1 shared
De Souza, W.
1 / 1 shared
Melo, Sa
1 / 1 shared
Granjeiro, Jm
1 / 1 shared
Ribeiro, Ar
1 / 3 shared
Rocha, La
1 / 2 shared
Dias, Mm
1 / 9 shared
Monteiro, Fj
9 / 15 shared
Manrique, Ya
1 / 2 shared
Salgado, Cl
2 / 3 shared
Souto Lopes, M.
1 / 1 shared
Santos, Tg
1 / 2 shared
Inacio, Pl
1 / 1 shared
Santos, C.
1 / 8 shared
Alves, P.
1 / 7 shared
Ferreira, Fb
1 / 1 shared
Alves, Mm
1 / 1 shared
Vidal, C.
1 / 2 shared
Carmezim, Mj
1 / 1 shared
Triches, Es
3 / 3 shared
De Siqueira, L.
3 / 3 shared
Daskalova, A.
1 / 6 shared
Trifonov, A.
1 / 3 shared
Buchvarov, I.
1 / 6 shared
Carvalho, A.
3 / 11 shared
Cunha Reis, C.
1 / 1 shared
Sousa, Sr
1 / 2 shared
Ribeiro, N.
1 / 2 shared
Paredes, Mba
1 / 1 shared
Sousa, Jc
1 / 1 shared
Cerqueira, F.
1 / 6 shared
Gabriel, C.
1 / 5 shared
Medeiros, R.
1 / 2 shared
Ferraz, Mp
3 / 6 shared
Dias, Am
1 / 6 shared
Ribeiro, Ai
1 / 4 shared
Proenca, Mf
1 / 1 shared
Caseiro, Ar
1 / 2 shared
Branco, M.
1 / 2 shared
Mauricio, Ac
1 / 5 shared
Gomes, Ps
12 / 14 shared
Pedrosa, Ss
1 / 1 shared
Rema, A.
1 / 1 shared
Amorim, I.
1 / 2 shared
Silva, Dm
3 / 4 shared
Sencadas, V.
3 / 110 shared
Santos, Jd
10 / 37 shared
Branquinho, Mv
1 / 1 shared
Lasgorceix, M.
1 / 5 shared
Monteiro, F.
1 / 5 shared
Hocquet, S.
1 / 2 shared
Ott, C.
1 / 4 shared
Cambier, F.
1 / 1 shared
Leriche, A.
1 / 2 shared
Boilet, L.
1 / 3 shared
Stamboulis, A.
1 / 6 shared
Nandyala, Sh
3 / 4 shared
Hungerford, G.
1 / 7 shared
Gouveia, Rf
1 / 1 shared
Cesar, Pf
1 / 1 shared
Miranda, Rbp
1 / 1 shared
Correia, Co
1 / 1 shared
Santos, D.
1 / 5 shared
Colaco, Bj
1 / 1 shared
Valente, Tam
1 / 1 shared
Bastos, Ac
1 / 3 shared
Belmonte, M.
1 / 16 shared
Silva, Rf
3 / 10 shared
Mata, D.
2 / 5 shared
Oliveira, Fj
2 / 5 shared
Neto, Ma
1 / 2 shared
Lopes, Ma
9 / 37 shared
Sooraj Hussain, Ns
1 / 2 shared
Morais, Ds
1 / 2 shared
Fernandes, S.
1 / 9 shared
Sampaio, Paula
2 / 7 shared
Costa, E.
1 / 10 shared
Laranjeira, Ms
1 / 1 shared
Santos Silva, A.
1 / 19 shared
Pelaez Vargas, A.
1 / 1 shared
Hansford, D.
1 / 1 shared
Coimbra, S.
1 / 1 shared
Araujo, Rf
1 / 1 shared
Ferreira, Nm
1 / 4 shared
Fernandes, Ajs
1 / 4 shared
Garcia, Mp
1 / 1 shared
Coelho, J.
2 / 16 shared
Nunes, Oc
1 / 4 shared
Pacheco, Ap
1 / 1 shared
Botelho, C.
1 / 1 shared
Vila, M.
1 / 4 shared
Silva, Ma
1 / 2 shared
Sooraj Hussain, N.
1 / 2 shared
Dias, Ag
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Cabral, Att
1 / 1 shared
Chart of publication period
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2018
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Co-Authors (by relevance)

  • Piperni, Sg
  • De Souza, W.
  • Melo, Sa
  • Granjeiro, Jm
  • Ribeiro, Ar
  • Rocha, La
  • Dias, Mm
  • Monteiro, Fj
  • Manrique, Ya
  • Salgado, Cl
  • Souto Lopes, M.
  • Santos, Tg
  • Inacio, Pl
  • Santos, C.
  • Alves, P.
  • Ferreira, Fb
  • Alves, Mm
  • Vidal, C.
  • Carmezim, Mj
  • Triches, Es
  • De Siqueira, L.
  • Daskalova, A.
  • Trifonov, A.
  • Buchvarov, I.
  • Carvalho, A.
  • Cunha Reis, C.
  • Sousa, Sr
  • Ribeiro, N.
  • Paredes, Mba
  • Sousa, Jc
  • Cerqueira, F.
  • Gabriel, C.
  • Medeiros, R.
  • Ferraz, Mp
  • Dias, Am
  • Ribeiro, Ai
  • Proenca, Mf
  • Caseiro, Ar
  • Branco, M.
  • Mauricio, Ac
  • Gomes, Ps
  • Pedrosa, Ss
  • Rema, A.
  • Amorim, I.
  • Silva, Dm
  • Sencadas, V.
  • Santos, Jd
  • Branquinho, Mv
  • Lasgorceix, M.
  • Monteiro, F.
  • Hocquet, S.
  • Ott, C.
  • Cambier, F.
  • Leriche, A.
  • Boilet, L.
  • Stamboulis, A.
  • Nandyala, Sh
  • Hungerford, G.
  • Gouveia, Rf
  • Cesar, Pf
  • Miranda, Rbp
  • Correia, Co
  • Santos, D.
  • Colaco, Bj
  • Valente, Tam
  • Bastos, Ac
  • Belmonte, M.
  • Silva, Rf
  • Mata, D.
  • Oliveira, Fj
  • Neto, Ma
  • Lopes, Ma
  • Sooraj Hussain, Ns
  • Morais, Ds
  • Fernandes, S.
  • Sampaio, Paula
  • Costa, E.
  • Laranjeira, Ms
  • Santos Silva, A.
  • Pelaez Vargas, A.
  • Hansford, D.
  • Coimbra, S.
  • Araujo, Rf
  • Ferreira, Nm
  • Fernandes, Ajs
  • Garcia, Mp
  • Coelho, J.
  • Nunes, Oc
  • Pacheco, Ap
  • Botelho, C.
  • Vila, M.
  • Silva, Ma
  • Sooraj Hussain, N.
  • Dias, Ag
  • Cabral, Att
OrganizationsLocationPeople

article

Inhibitory Effect of 5-Aminoimidazole-4-Carbohydrazonamides Derivatives Against Candida spp. Biofilm on Nanohydroxyapatite Substrate

  • Sousa, Jc
  • Cerqueira, F.
  • Monteiro, Fj
  • Gabriel, C.
  • Medeiros, R.
  • Ferraz, Mp
  • Dias, Am
  • Fernandes, Mh
  • Ribeiro, Ai
  • Proenca, Mf
Abstract

Candida can adhere and form biofilm on biomaterials commonly used in medical devices which is a key attribute that enhances its ability to cause infections in humans. Furthermore, biomaterial-related infections represent a major therapeutic challenge since Candida biofilms are implicated in antifungal therapies failure. The goals of the present work were to investigate the effect of three 5-aminoimidazole-4-carbohydrazonamides, namely (Z)-5-amino-1-methyl-N '-aryl-1H-imidazole-4-carbohydrazonamides [aryl = phenyl (1a), 4-fluorophenyl (1b), 3-fluorophenyl (1c)], on Candida albicans and Candida krusei biofilm on nanohydroxyapatite substrate, a well-known bioactive ceramic material. To address these goals, both quantitative methods (by cultivable cell numbers) and qualitative evaluation (by scanning electron microscopy) were used. Compounds cytocompatibility towards osteoblast-like cells was also evaluated after 24 h of exposure, through resazurin assay. The three tested compounds displayed a strong inhibitory effect on biofilm development of both Candida species as potent in vitro activity against C. albicans sessile cells. Regarding cytocompatibility, a concentration-dependent effect was observed. Together, these findings indicated that the potent activity of imidazole derivatives on Candida spp. biofilms on nanohydroxyapatite substrate, in particular compound 1c, is worth further investigating. [GRAPHICS] .

Topics
  • impedance spectroscopy
  • compound
  • scanning electron microscopy
  • ceramic
  • biomaterials